Video-based Machine Rating Model for MDS-UPDRS III in Parkinson’s disease: A Proof-of-concept Pilot Study
Objective: To develop a video-based machine rating system for the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) III. Background: MDS-UPDRS III…Codesigning Tech with Patients – Insights from the Quantitative and Qualitative Analysis of Three Technologies used in Patients With Parkinson’s Disease
Objective: To evaluate the usability and acceptability of three different digital health technologies developed for Parkinson's disease (PD). Background: PD care requires meeting patients' changing…Free-living digital mobility outcomes in Parkinson’s disease patients with and without freezing of gait: what can they tell us?
Objective: I) To compare digital mobility outcomes (DMOs) of free-living gait quality and quantity obtained over one week between people with Parkinson’s disease (PwPD) who…Gait and turning during daily life across the spectrum of normal, prodromal, early and moderate Parkinson’s disease
Objective: To compare gait and turning quality during daily life in older adults, people with Rapid Eye Movement (REM) sleep behavior disorder (RBD) and people…The functional consequences of the ‘African GBA1 allele’ of rs3115534 in Parkinson’s Disease
Objective: To gain insights into the pathophysiology by which the G-allele of rs3115534 confers risk for PD. Background: A recent paper defined the G-allele of…Long-read sequencing to identify unrevealed second hit in autosomal recessive Parkinson’s disease
Objective: Identify unrevealed variants in PRKN and PINK1 genes from young onset Parkinson’s disease (YOPD) patients. Background: Long-read sequencing has identified pathogenic repeats and structural…Strategic Training Framework for Advancing Research Capacity through GP2
Objective: To promote and facilitate learning by providing resources and expertise to address the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org) and…Frequency of LRRK2 p.L1795F variant in Parkinson’s Disease patients from Central Europe within the CEGEMOD consortium
Objective: The aim of this study was to investigate the presence of LRRK2 p.L1795F variant in PD patients from Central Europe. Background: Pathogenic variants in…The association of Severity and Monogenetic Subgroups in Parkinson’s Disease
Objective: Explore how different genotypes can affect the disease severity and progression in Parkinson's patients. Background: Genetic advances have identified specific mutations linked to disease…Personalized Optimization of Deep Brain Stimulation Parameters for Gait Enhancement in Parkinson’s Disease: A Data-Driven Approach
Objective: Our goal is to develop a data-driven approach to identify optimal Deep brain stimulation (DBS) parameters for gait enhancement in patients with Parkinson's disease…
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