Uncovering the mechanisms of genotype by environment interaction in an idiopathic Parkinson’s disease model in Drosophila
Objective: To identify the genetic basis and the molecular mechanisms that underlie the susceptibility of developing motor defects in response to exposure to pesticides in…Clinical analysis of Levodopa/carbidopa intestinal gel infusion in advanced Parkinson’s disease. A single-center retrospective cohort study.
Objective: To evaluate clinical impact of treatment (LCIG) infusion in patients with advanced PD. Background: Levodopa/carbidopa intestinal gel (LCIG) infusion has demonstrated more stable plasma…Harmonizing genetic testing for early-onset Parkinson’s disease: results of the PARKNET multicentric study
Objective: To harmonize the interpretation of genetic testing in Parkinson's disease (PD) across the PARKNET network, as well as to provide a comprehensive assessment of…10 year longitudinal change in clinical and biological characteristics of sporadic Parkinson Disease PPMI cohort
Objective: To present data on 10 year longitudinal clinical and biological characteristics of sporadic Parkinson Disease (sPD) participants in the Parkinson’s Progression Markers Initiative (PPMI)…Modulation of a subthalamic nucleus related network associated with motor response following Deep Brain Stimulation
Objective: To identify a network associated with the therapeutic effects of STN DBS Background: The network topography associated with the therapeutic effects of STN DBS…Telemedicine challenges in the management of patients with Parkinson’s disease in Central Asia.
Objective: The aim of the study is to identify challenges for telemedicine in treatment among patients with parkinsonism in Kyrgyzstan and Kazakhstan. Background: The covid-19…The role of genetic factors in the occurrence of levodopa-induced motor complications in Parkinson’s disease
Objective: We aimed to evaluate the association of selected polymorphisms of COMT, DRD2, ANKK1, and DAT genes and the occurrence of levodopa-induced motor complications in…Levodopa-Entacapone-Carbidopa Intestinal Gel in advanced Parkinson’s disease: a single center experience
Objective: To evaluate the efficacy of Levodopa-Entacapone-Carbidopa Intestinal Gel (LECIG) in achieving adequate control of motor complications in patients with advanced Parkinson’s Disease (APD). Background:…Subthalamic stimulation reshapes the reliable inherent brain state in Parkinson’s disease
Objective: To elucidate the reliable inherent state of resting-state global brain network and explore the state modulation mechanism of subthalamic stimulation (STN-DBS) on Parkinson’s disease…Long-term effectiveness of adjuvant treatment with catechol-o-methyltransferase or monoamine oxidase B inhibitors compared with dopamine agonists in Parkinson’s disease uncontrolled by levodopa: final results of the PD MED LATER randomized clinical trial
Objective: PD MED LATER is a large, pragmatic trial aiming to determine which class of drug when added to levodopa provides the most effective control…
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