The Global Parkinson’s Genetics Program (GP2) Underrepresented Populations Working Group
Objective: GP2's Underrepresented Populations Working Group (WG) was created for individuals working within underrepresented/underserved populations to join forces to increase global representation and decipher the…Integrated Multi-omics of the Gut Microbiome Reveal 2-Hydroxypyridine as a Novel Molecule Relevant to Parkinson’s Disease Pathogenesis
Objective: To search for molecular links between Parkinson’s disease (PD) pathogenesis and gut microbes based on integrated multi-omic analyses of fecal samples from patients with…Neurofilament light chain serum levels in E46K-SNCA mutation carriers
Objective: To demonstrate the usefulness of measuring the concentration of neurofilament light chain (NfL) in blood using Single Molecule Array matrix (SiMoA, Quanterix) as a…Interest of optical coherence tomography in Parkinson’s disease
Objective: To compare optical coherence tomography (OCT) results of retinal thickness (RT) and retinal nerve fiber layer (RNFLT) thickness of patients with idiopathic Parkinson's disease…Insulin resistance and Parkinson’s disease
Objective: To investigate peripheral insulin resistance and cerebral FDG-PET changes in Parkinson’s disease (PD). Background: Glycated hemoglobin levels (HbA1c) is used as a marker of…Altered functional connectivity of the hippocampus in posterior-cortical subtype of cognitive impairment in Parkinson’s disease
Objective: We aimed to delineate the dual syndrome subtypes of PD-MCI using a data-driven approach and explore hippocampal functional connectivity of the posterior-cortical syndrome. Background:…Resting state functional MRI network assortativity is increased in Parkinson’s disease
Objective: In previous imaging studies, we have that patients with Parkinson’s disease (PD) express a distinct brain network known as the Parkinson’s disease-related pattern (PDRP).…Deficient interhemispheric connectivity underlies movement irregularities in Parkinson’s disease
Objective: The aim of this study was to investigate whether impaired execution of drawing spirals relates to deteriorations in interregional connectivity. Background: Movement execution is…The impact of fatigue and pain on functional mobility, fear of falling, and falls in Individuals with Parkinson’s disease
Objective: This is a cross-sectional pilot study aiming to examine: (1) the relationship of fatigue and pain with functional mobility, fear of falling (FOF), and falls in individuals with Parkinson's disease (PD), (2) differences in fatigue and pain between PD fallers and non-fallers, and (3) distinguishing…Effects of Parkinson’s disease on blur-driven and disparity-driven vergence eye movements
Objective: Visuomotor functions required for depth and dimensionality perception are significantly affected in a large number of patients with Parkinson’s disease (PD). Vergence is a…
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