Structural connectivity affecting freezing of gait after globus pallidus internus deep brain stimulation in Parkinson’s disease
Objective: We aim to investigate how structural connectivity of the brain affects gait freezing after globus pallidus internus (GPi) deep brain stimulation (DBS). Background: Freezing…Facial emotion recognition in Parkinson’s disease: the role of executive and affective domains
Objective: We aimed to explore facial emotion recognition (FER) skills in individuals with Parkinson’s disease (PD) by using a dynamic presentation of emotions across different…Double trouble: Association of malignant melanoma with sporadic and genetic forms of Parkinson’s disease and asymptomatic carriers of related genes in the PPMI study.
Objective: The aim of the present study was to assess the prevalence of malignant melanoma (MM) in sporadic and genetic Parkinson’s disease (PD) patients and…The Genetic Landscape of Parkinson’s disease in populations of non-Caucasian ancestry.
Objective: We aimed to review existing literature on the genetic background of Parkinson’s disease (PD) populations of non-Caucasian or mixed ancestry. Background: There has been…In Silico Study Reveals Cocaine Exposure Modulates Dopamine Neuron Firing Patterns by Inhibiting Small Conductance Calcium Activated Potassium Current
Objective: The neurological reason behind the loss of dopamine neurons causing Parkinson’s disease (PD) is an unsolved mystery. Background: As PD is identified as a…Optimizing patient-centric clinical outcome assessments for use in Parkinson’s disease clinical trials: Critical Path for Parkinson’s multistakeholder initiative
Objective: To advance patient-centric endpoints for use in early-stage Parkinson’s disease (PD) clinical trials. Background: Limitations with currently available patient-centric clinical outcome assessments (COAs) has…Factors related to the antidepressant effect of safinamide in Parkinson’s disease. A post-hoc analysis of SADNESS-PD study
Objective: To assess the role of different factors in the antidepressant effect of safinamide in Parkinson’s disease (PD) Background: SADNESS-PD was a real-life, multicenter, retrospective…Alprazolam reduces freezing of gait and improves freezing-related gait measures
Objective: We investigated the effect of acutely reducing anxiety with the benzodiazepine, Alprazolam, on freezing of gait (FOG) in patients with Parkinson’s disease (PD). Background:…Relationship between gait speed and functional measurements in Parkinson’s disease
Objective: The present study aims to relate gait speed in Parkinson's disease (PD) with functional measures of muscle strength, balance and physical capacity. Background: PD…Rapid onset of good ON time and improvement in motor-state stability in aPD patients after treatment with continuous subcutaneous foslevodopa/foscarbidopa
Objective: To evaluate time to ON without troublesome dyskinesia (‘good ON’) and patterns of motor-state stability throughout the day in patients with advanced Parkinson’s disease…
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