Pilot study to investigate the use of in-clinic sensing to identify optimal stimulation parameters for deep brain stimulation therapy in Parkinson’s disease
Objective: Compare the use of in-clinic sensing functionality and standard of care monopolar review for identifying optimal settings of a deep brain stimulation (DBS) in…Parkin deficiency impairs mtDNA dynamics and propagates inflammation
Objective: We sought to explore Parkin’s role in (i) averting neuronal mtDNA dyshomeostasis/release and (ii) the activation of downstream inflammatory processes. Background: Mutations in Parkin…Challenges in Outcome Measure Selection in Multi-Arm Multi-Stage Clinical Trials in Parkinson Disease
Objective: The Edmond J Safra Accelerating Clinical Trials in Parkinson Disease (PD) initiative (EJS ACT-PD) aims to accelerate the identification of disease modifying treatment for…Oligomeric alpha-synuclein in reflex tears and retinal changes in Parkinson’s disease
Objective: To compare oligomeric alpha-synuclein (α-Syn) in reflex tears and its association with the thickness of retinal layers in Parkinson’s disease (PD) Background: Alpha-synuclein is…Effects of Parkinson’s disease and freezing of gait on the kinematic and kinetic gait parameters
Objective: This study aims to evaluate the effects of Parkinson's disease and freezing of gait (FoG) on the kinematic and kinetic gait parameters, both in…Evaluation of ocular perfusion in Parkinson’s disease and association with clinical manifestations.
Objective: To evaluate optic nerve head and macular perfusion in subjects with Parkinson's disease (PD) and its association with clinical manifestations. Background: PD is associated…Validation of the English version of the Parkinson Anxiety Scale in the Canadian population: Interim results
Objective: To validate the use of the English version of the PAS in Parkinson’s disease (PD) patients in Canada. Background: The PAS, originally developed to…Perturbation-based balance training in individuals with Parkinson’s disease and freezing of gait
Objective: In the current study, we assessed the effect of a multisession training program based on unpredictable AP and ML perturbations of body balance on…Impact of SARS-CoV-2 vaccine in Parkinson’s disease
Objective: To evaluate the impact of SARS-CoV-2 vaccine on motor and non-motor symptoms in Mexican people with Parkinson's disease (PwP). Background: Nowadays, as a consequence…Fundamental changes in Nerve Conduction Velocity and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in a chronic PD in vivo model: a neurotool for Parkinson’s disease diagnosis
Objective: To evaluate the changes in NCV and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in MPTP induced chronic PD…
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