Platelets Lipidome as Potential Biomarker of Parkinson’s Disease
Objective: The aim of this proejct is to identify novel biomarkers of Parkinson's disease diagnosis and progression, with a focus on GBA-PD. Background: Our previous…Paradoxical Association of Kinetics of α-Synuclein Seed Amplification 24-hrs Assay and Clinico-Pathological Markers of Parkinson’s disease
Objective: To investigate the association between baseline α-synuclein seed amplification assay (SAA) parameters and clinical and biomarker features of Parkinson’s disease (PD) at baseline and…Eye movement abnormalities in GBA1-related Parkinson’s disease and non-manifesting GBA1-carriers
Objective: To perform an in-depth characterization of eye movement abnormalities in Parkinson’s disease (PD) and non-manifesting carriers of GBA1 pathogenic variants. Background: Eye movement abnormalities…Amplification Parameters of the Alpha-Synuclein Seed Amplification Assay on CSF Predict the Clinical Subtype of Parkinson’s Disease at 10-Year Follow-Up
Objective: To assess the association between the parameters of alpha-synuclein seed amplification assay on CSF (CSF-αSyn-SAA) within 2 years from Parkinson’s disease (PD) onset and…Stratification study of alpha-synucleinopathy by body fluid biomarkers
Objective: This study aims to stratify patients with Parkinson's disease (PD) based on clinical features and several disease-associated biomarkers by analyzing the relationship between biomarkers,…Predictors of Health-Related Quality of Life in Parkinson’s Disease: A Five-Year Longitudinal Study
Objective: The aim of this study was to identify the predictors for health-related quality of life (HRQoL) in Parkinson´s disease (PD) in a 5-year longitudinal…Are Hallucinations in Parkinson’s Driven by Over-Reliance on Prior Information?
Objective: Test the validity of a theoretical model that visual hallucinations in Parkinson’s arise from over-reliance on prior information. Background: Parkinson’s hallucinations are common and…Design of the Phase 2, Double-Blind, Placebo-Controlled, Multicenter Study Investigating the Efficacy and Safety of ACP-204, a Novel 5-HT2A Inverse Agonist, in Adults With Lewy Body Dementia Psychosis
Objective: To present the design for a study of ACP-204 efficacy and safety in adults with Lewy body dementia psychosis (LBDP), including Parkinson’s disease dementia…Pilot Feasibility Data using Augmented Reality and Machine Learning-Based Digital Cognitive Assessment in Parkinson’s disease
Objective: To assess the feasibility of using a novel cognitive and functional digital biomarker assessment, the Altoida NeuroMarker platform, to evaluate the presence of MCI…What women want: real-life experiences of women with Parkinson’s disease
Objective: To explore the experiences of women with Parkinson’s disease (WwPD) in healthcare access, physical and mental health, relationships, and future planning, identifying unmet needs.…
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