Multimodal Deep Learning for Parkinson’s Disease Screening: Fusing Quantitative Gait Analysis and Clinical Features
Objective: To develop and validate a machine learning model integrating quantitative gait parameters and clinical features to enhance the diagnostic accuracy of Parkinson's disease (PD)…Subthalamic Nucleus Oscillatory Coupling During Sleep is Impaired in Parkinson’s Disease and Associated with Memory Consolidation
Objective: To investigate whether the subthalamic nucleus (STN) supports sleep-dependent memory consolidation through hierarchical oscillatory coupling, and whether this mechanism is disrupted in Parkinson's disease…Longitudinal cognitive trajectories and predictors of dementia conversion in Parkinson’s disease
Objective: To determine clinical predictors of longitudinal cognitive decline and dementia conversion in a real-world Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of…Device-aided Therapies are Associated with Significantly Greater Improvement in Quality of Life in Younger Patients Earlier Within Advanced Parkinson’s Disease
Objective: To evaluate the impact on health-related quality of life (HRQoL) of treatment with device-aided therapies (DAT) in younger patients earlier within advanced Parkinson's disease…Attention-Enhanced Deep Learning for Midbrain MRI Segmentation in Parkinson’s Disease
Objective: To develop an automated deep learning framework for robust midbrain segmentation in MRI data of Parkinson’s disease patients. Background: Structural alterations in the midbrain…Characteristics And Progression Of Non-Motor Symptoms In Parkinsons Disease
Objective: The aim of this study is to investigate the characteristics and the progression of different domains of NMS in PD, and to determine their…Item – Level Drivers of Certification Failure in the MDS-UPDRS Motor Examination: A Five-Year Global Analysis
Objective: To identify individual Part III items that disproportionately contribute to first-attempt certification failure and to evaluate the stability of these patterns over five years.…The Diagnostic Value of Dopaminergic-Glucose United PET Imaging in Parkinson’s disease
Objective: This study aimed to evaluate the diagnostic efficacy of DAT-FDG united PET imaging in differentiating PD from other parkinsonian disorders in real-world clinical settings…Prospective Evaluation of a Video-Based Motor Assessment Workflow: Feasibility, Usability, and Data Quality
Objective: To prospectively evaluate the feasibility, usability, and data quality of a video-based motor assessment platform (PRIMS) in a clinic setting, and to examine agreement…Fear Across the Disease Course: How Age, Sex, and Disease Duration Influence Different Types of Fear in Parkinson’s Disease
Objective: 1. To determine the prevalence of different fear types in people with Parkinson’s disease (PwP) and their perceived impact on daily activities. 2. To…
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