DJ-1 (PARK7) Heterozygous Mutation and Early-Onset Parkinson’s Disease: A Chilean Case Report and Literature Review
Objective: We report a Chilean patient with childhood-onset Parkinson’s disease (PD) carrying a single heterozygous PARK7 (DJ-1) mutation and review its clinical and pathophysiological relevance.…Effect of ApoE ε4 allele on brain metabolism and cognition in non-demented Parkinson’s disease
Objective: This study aimed to explore the interplay between Apolipoprotein E (ApoE) ε4 allele, brain metabolism, and cognition in non-demented Parkinson’s disease (PD) patients. Background:…Standardised Home-Based Walk Tests Can Capture Gait Differences in Parkinson’s Disease Using Wearable Sensors
Objective: To evaluate the feasibility and discriminative utility of a standardised home-based walk test using wearable sensors in people with Parkinson's disease (PwP). Background: Wearable…Characterisation of early onset Parkinson’s disease in UK cohorts
Objective: To identify and describe the genetic features of UK early onset Parkinson’s disease (EOPD) patients. Background: EOPD with age of onset (AAO) <36 years…Fibrinogen and CFAH as putative biomarkers for Parkinson’s disease
Objective: To examine the levels of putative biomarkers FIB, CFAH, gelsolin (GSN), α-syn and phosphorylated-α-syn in PD serum. To localize and quantify FIB and CFAH in…Segment-Level Gait Dynamics Reveal Parkinsonian Motor Signatures in Fall-Prone Older Adults Using Multi-Channel Time–Frequency Deep Learning
Objective: To develop a multi-channel time–frequency deep learning framework capable of identifying Parkinsonian gait dynamics from short locomotor segments and detecting PD-like motor state transitions…Sex Differences in Prodromal Features of Parkinson’s Disease: Evidence from Large Multi-Centre Cohorts
Objective: To explore sex differences in symptoms of prodromal Parkinson’s disease (PD) in large, population-based multi-centre cohorts of healthy individuals, PREDICT-PD and Healthy Brain Ageing…Clinical instability and fluctuations as an early marker of accelerated progression
Objective: To determine whether early clinical instability, quantified through combined motor and non-motor fluctuations, predicts a more severe longitudinal disease course in Parkinson’s disease. Background:…Does Knowing More Mean Tolerating More? Satisfaction with Medication Information and Levodopa Dosage in Parkinson’s Disease
Objective: To characterize the correlation between satisfaction with medication-related information and daily levodopa dosage in Parkinson’s disease (PD) patients presenting with levodopa-related complaints. Background: Adequate…Impulse-compulsive disorders and non-motor symptom profiles in Parkinson’s disease: findings from a Tunisian cohort
Objective: To examine the relationship between impulse-compulsive disorders (ICDs) and non-motor symptom profiles in patients with Parkinson’s disease (PD). Background: ICDs are recognized non-motor complications…
- « Previous Page
- 1
- …
- 84
- 85
- 86
- 87
- 88
- …
- 553
- Next Page »