Unnecessary Ablative Surgery in an Untreated Parkinson’s Disease Patient: Marked Clinical Improvement After Initiation of Dopaminergic Therapy
Objective: To report a case of Parkinson’s disease (PD) in which two ablative procedures were performed without prior dopaminergic therapy, followed by significant clinical improvement…Risk factors for dysautonomic fluctuations in Mexican PwP
Objective: To identify risk factors for non-motor dysautonomic fluctuations in people living with Parkinson’s disease (PwP). Background: Advanced Parkinson’s disease (PD) is characterized by motor…Levodopa Initiation in Phase 3 Trials of Tavapadon, a Selective D1/D5 Agonist for Early Parkinson’s Disease
Objective: To evaluate motor improvements in adults with early Parkinson’s disease (PD) who initiated levodopa (LD) during phase 3 trials of tavapadon. Background: Tavapadon, an…Engage-Qatar PD (EQP): Pilot RCT of a Remote Coaching Intervention Using Online Platform to Promote Engagement in Physical Activity in People with Parkinson’s Disease in Qatar.
Objective: Evaluate the effect of the EQP program, on Physical Activity (PA) participation and functional walking capacity among people with Parkinson’s disease (PwP) compared with…Dynamics of Motor Fluctuations and Medication Challenges in Parkinson’s Disease
Objective: To investigate the dynamics of tremor, bradykinesia, and finger dexterity during the OFF-to-ON transition using objective measures. Additionally, assesses medication administration challenges through a…Determinants of Quality of Life According to Brain-first and Body-first in Patients with Parkinson’s Disease
Objective: In this study, we aimed to investigate the potential determinants of QoL in brain-first and body-first patients with PD. Background: Parkinson’s disease (PD) is…Integrating Transcriptomics and Morphological Profiling to Characterize GBA-Associated Parkinson’s Disease in Midbrain Organoids
Objective: This study characterizes converging biological trends in GBA-associated Parkinson’s Disease by integrating transcriptomic profiling with exploratory image-based analysis of donor-matched midbrain organoids. Background: High-content…Sleep Disorders and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To comprehensively evaluate the association between various sleep disorders and the risk of developing Parkinson’s disease. Background: Sleep disturbances are increasingly recognized as important…Real-Time Quaking-Induced Conversion Detection of Tear Fluid α-Synuclein as a Potential Biomarker for Parkinson’s Disease
Objective: To detect α-synuclein (aSyn) in tear fluid and to evaluate the clinical characteristics of aSyn-positive patients. Background: Parkinson's disease (PD) is an α-synucleinopathy. Pathological…Neurotwain: Extended-reality based virtual brain imaging for one-stop-shop diagnosis and progression of Parkinson’s Disease
Objective: We propose a new non-invasive, wearable, ambulatory, and cost-effective virtual imaging platform, Neurotwain, to screen individuals and obtain a baseline test to evaluate risk…
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