Characterization of autonomic dysfunction in prodromal and early stages of Parkinson’s Disease
Objective: To evaluate cardiovascular autonomic dysfunction across prodromal stages of synucleinopathies (Pure Autonomic Failure-PAF); isolated REM Sleep Behavior Disorder-iRBD) and early stages of Parkinson’s disease…Motor & Non-Motor Symptoms in nOH & RBD
Objective: To assess whether the co-occurrence of neurogenic orthostatic hypotension (nOH) and REM sleep behavior disorder (RBD) is associated with a more severe clinical presentation…Functional Alterations in Early-Stage Parkinson’s Disease and Multiple System Atrophy with REM Sleep Behavior Disorder
Objective: This study investigated functional brain network alterations in early-stage Parkinson’s disease (PD) and multiple system atrophy (MSA) patients with probable rapid eye movement sleep…Semantic Memory Deficit as a Potential Risk Factor of Dementia in Isolated Rapid Eye Movement Sleep Behavior Disorder
Objective: We aimed to evaluate semantic memory (SM) performance in isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) and identify the specific profile of…Opicapone in Parkinson’s Patients with Probable REM Sleep Behavior Disorder: Insights from the OASIS Trial
Objective: To evaluate opicapone’s effect on sleep disturbances, motor and non-motor symptoms and quality of life in Parkinson's disease (PD) patients with and without probable…Clinical Progression and Genetic Pathways in Body-First and Brain-First Par-kinson’s Disease
Objective: We aim to assess Parkinson's disease (PD) phenotypes across both prodromal and clinical PD stages, track their pathological progression in vivo and identify potential underlying…Sleep-wake Alterations are Associated with a Decreased DTI-ALPS, a Marker of Perivascular Glymphatic Functioning, in Patients with Isolated REM Sleep Behavior Disorder
Objective: We aimed to explore circadian disruption in iRBD and its association with the Diffusion Tensor Imaging- ALong the Perivascular Space (DTI-ALPS) index, a proxy…Color Vision In Patients With Clinical Manifestations Of Rem Sleep Behavior Disorder
Objective: To evaluate the presence of changes in color vision in patients with REM sleep behavior disorder (RBD), Parkinson's disease (PD), and controls. Background: Visual…Eye tracking identifies biomarkers predicting Parkinson’s disease before motor symptom onset
Objective: To investigate eye movement changes as an early motor biomarker of Parkinson’s disease (PD) in patients with REM sleep behavior disorder (RBD). Background: RBD…Plasma Lipids as Potential Biomarkers for Progression of Sleep Disturbances in Parkinson’s Disease
Objective: Determine if plasma lipid levels can serve as a surrogate biomarker of future onset of RBD symptoms or nighttime sleep burden in patients with…
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