Baicalein Attenuates Rotenone-Induced Neurodegeneration by Regulating BDNF/CREB/Akt Signaling in Parkinson’s Disease
Objective: To evaluate the therapeutic potential of baicalein and to investigate its underlying neuroprotective mechanism in a rotenone-induced mouse model of Parkinson’s disease. Background: Parkinson’s…Aerva Lanata Decoction Alleviates Neuroinflammation And Locomotor Dysfunction In Parkinson Model
Objective: The study focussed on the protective effects of decoction of aerial parts of the Aerva lanata against neuroinflammation, oxidative stress and locomotor deficits against…Screening the Neuroprotective Potential of Mushroom Extracts in In Vitro Models of Parkinson’s Disease
Objective: This study aimed to evaluate the neuroprotective potential of various mushroom extracts across four distinct cellular models of PD. Furthermore, we sought to identify…Evaluation of Neuroprotective Effect of Terminalia macroptera on Rotenone Induced Parkinson’s Disease in Mice
Objective: This study investigates the neuroprotective effects of an aqueous extract of Terminalia macroptera (AETM) in a rotenone-induced Parkinsonism mouse model. Background: Parkinson’s disease (PD)…Carvacrol modulates rotenone-induced Nigrostriatal Neuronal Death and Angiogenesis via targeting AMPK/FOXO3 transcription factor O3 Signaling cascade
Objective: With an eye toward its effects on striatal angiogenesis and the AMPK/ FOXO3 transcription factor O3 pathway, this work attempts to investigate the neuroprotective…Phosphorylated High Mobility Group Box Protein 2 (HMGB2) as a Potential Biomarker for Parkinson’s Disease
Objective: We recently showed that HMGB2 is secreted during ferroptosis and as ferroptosis is involved in the etiology of PD, we have examined the possibility…Vitamin D3 Supplementation Ameliorates Non-Motor Symptoms Associated with Parkinson’s Diseases in a Rotenone Model in Wistar Rats
Objective: This study investigated the role of VD3 supplementation on non-motor symptoms and its mechanism of action in a rotenone rat model of PD. Background:…Manganese-induced Parkinsonism Vs Rotenone-induced Parkinsonism: Animal Life Matters!
Objective: To evaluate the Parkinsonism mimicking potential of MnCl2 in an experimental rat model.To compare the destructive effect of MnCl2 with rotenone by performing behavioral,…Systematic Review and Meta-Analysis of Pesticide Exposure and the Risk of Parkinson’s Disease
Objective: This study aimed to investigate the association between exposure to pesticides and the risk of Parkinson’s disease (PD). Background: PD is the second most…Neuroprotective Effect of Isoquercitrin in Rotenone Induced Parkinson’s Disease-Like Motor and non-motor Symptoms in Zebrafish
Objective: The objective of study is to find out the effect of isoquercitrin, a plant-derived chemical, against Parkinson-like symptoms induced by rotenone in zebrafish.. Background:…
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