An explorative study on the value of clinical features for diagnosing Parkinson’s disease
Objective: To investigate the usefulness of clinical features to differentiate subjects with “scans without evidence of dopaminergic deficit” (SWEDD) from patients presumed to have Parkinson’s…No link between striatal dopaminergic axons and dopamine transporter imaging in Parkinson’s disease
Objective: The objective of this study was to investigate if dopamine transporter (DAT) binding is associated with dopaminergic neurites in the putamen. Background: Dopamine transporter…Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…Association between sleep disturbances in Parkinson’s disease and bioimaging
Objective: We investigated whether bioimaging for Parkinson’s disease (PD) such as metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 123I-ioflupane SPECT (DaTSPECT) are useful for biomarker of sleep…Correlation between Pareidolia and cerebral perfusion by SPECT in Parkinson’s disease without dementia: A retrospective study
Objective: The aim of this study is to investigate the correlation between the number of illusory responses on the Pareidolia test and cerebral perfusion in…Automated Interpretation of FP-CIT-SPECT images based on Artificial Intelligence
Objective: Our objective is to develop an AI-based approach to automatically rate FIP-CIT-SPECT data. Background: FP-CIT-SPECT visualizes the integrity of nigro-striatal dopaminergic synapses in vivo.…Striatal dopaminergic regulation of micrographia in parkinsonism
Objective: To investigate the role of brain dopamine function in writing and drawing micrographia of patients with parkinsonism. Background: Micrographia, an abnormally small or progressively…Relations of clinical symptoms with dopamine transporter imaging in untreated Parkinson’s disease
Objective: The aim of the present study was to determine the relations of clinical symptoms with nigrostriatal neuron loss in untreated patients with Parkinson's disease…123I-FP-CIT SPECT imaging in early PD patients versus mid and late onset PD: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in dopaminergic denervation [as exemplified by signal reduction in 123I-FP-CIT SPECT] in early PD patients versus mid…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…
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