MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Striatum"

  • 2026 International Congress

    Behavioral Phenotype of a Mouse Model of Mixed Movement Disorders Linked to ADCY5

    J. Baik, E. Conabady, M. Doulazmi, R. Yuan, C. Dubacq, E. Roze (Paris, France)

    Objective: To define the motor and non-motor phenotypic features of a novel Adcy5R419W mouse line [1] and validate it as an integrated model of human mixed movement disorders…
  • 2026 International Congress

    Trancranial Sonography Reveals Striatal Neurodegeneration in the Prodromal Phase of X-linked Dystonia-Parkinsonism

    M. Pauly, C. Diesta, P. Cataniag, M. Borsche, H. Hanssen, J. Ong, JQ. Oropilla, U. Walter, D. Dressler, S. Algodon, A. Westenberger, C. Klein, N. Brüggemann (Lübeck, Germany)

    Objective: To use transcranial sonography (TCS) to detect striatal and substantia nigra abnormalities in patients with X-linked dystonia-parkinsonism syndrome (XDP), non-manifesting carriers (NMC) of the…
  • 2026 International Congress

    Longitudinal shifts in goal-directed and habitual control relate to tic severity and cortico-striatal connectivity in adolescents with Tourette syndrome

    C. Lecomte, TM. Sartoris, C. Atkinson-Clement, B. Beranger, C. Tarrano, FX. Lejeune, R. Valabrègue, A. Hartmann, V. Czernecki, E. Roze, C. Rosso, P. Pouget, C. Gallea, Y. Worbe (Paris, France)

    Objective: To investigate the balance between goal-directed and habitual control in adolescents with Tourette syndrome (TS) and to determine how longitudinal changes in this balance…
  • 2026 International Congress

    A Novel Hyperkinetic–Cerebellar Phenotype with Subependymal Nodules in Glutaric Acidemia Type 1

    D. Avecilla-Bonilla, K. Salinas-Barboza, D. Ramírez álvarez, L. Salinas-Yañez, J. Altamirano (Mexico, Mexico)

    Objective: To describe an unusual phenotype in Glutaric Acidemia Type 1 (GA1) characterized by a hyperkinetic movement disorder, cerebellar syndrome, and subependymal nodules, expanding the…
  • 2026 International Congress

    Low-dose ketamine reduces dopamine 2 receptor-like agonist-induced dyskinesia in a preclinical model

    T. Falk, R. Parmar, J. Meredith, J. Castro, E. Smith, M. Bartlett, S. Sherman (Tucson, USA)

    Objective: Preclinical evaluation of low-dose ketamine treatment on dyskinesia induced by direct or indirect striatofugal pathway activation. Background: Ketamine infusions are effective therapy for depression…
  • 2026 International Congress

    Effects of Chronic IEM-1460 Treatment on Perineuronal Net–Parvalbumin Interneuron Association in L-DOPA-Induced Dyskinesia

    NT. Bilbay, EN. Kaptan, C. Cakir-Aktas, G. Yalcin-Cakmakli, B. Elibol, BC. Tel (Ankara, Turkey)

    Objective: To determine whether chronic IEM-1460 administration alters dyskinesia and perineuronal net (PNN)–parvalbumin interneuron (PV-IN) association in a 6-OHDA rat model of L-DOPA-induced dyskinesia (LID).…
  • 2026 International Congress

    Reversible Uremic Striatopathy Presenting as Acute Generalized Myoclonus and Chorea in a Patient with End Stage Renal Disease: A video-case report

    L. Parajiya, A. Doshi, D. Kapoor, S. Sheth, A. Aggarwal (Mumbai, India)

    Objective: To highlight uremic striatopathy as a reversible metabolic cause of acute hyperkinetic movement disorder in patients with end stage renal disease. Background: Uremic striatopathy…
  • 2025 International Congress

    Modulation of working memory in prodromal DLB by non-invasive brain stimulation of the striatum and cerebellum

    I. Rektorová, M. Pupikova, . Gajdoš (Brno, Czech Republic)

    Objective: We aimed to modulate working memory (WM) in patients with MCI with Lewy bodies (MCI-LB) by non-invasive stimulation of the striatum with or without…
  • 2025 International Congress

    Neuroimaging abnormalities of the striatopallidal regions in people with diabetes: A single-center retrospective study

    N. Chunga, A. Gershteyn, K. Palermo-Cruz, R. Ramchandran, G. Schifitto, K. Lizarraga (Rochester, USA)

    Objective: To describe the imaging abnormalities affecting striatopallidal regions (SP; caudate, putamen, and globus pallidum) in people with diabetes mellitus (DM). Background: DM can lead…
  • 2025 International Congress

    Microstructural Changes in the Striatum Correlate With Clinical Symptoms in Wilson Disease

    A. Hausmann, S. Querbach, C. Rubbert, A. Schnitzler, J. Caspers, C. Hartmann (Düsseldorf, Germany)

    Objective: To evaluate microstructural changes in the dorsal striatum and their correlation with clinical symptoms in Wilson disease (WD). Background: Advanced diffusion models, including Neurite…
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