Arginase2 – a potential mediator in the pathology of the stratum
Objective: To investigate the effects of arginase 2 (Arg2) loss on the striatal mitochondria. Background: Arginase plays a role in the production of various metabolites…Diabetic Striatopathy Treated with Tetrabenazine: A Case Report and Discussion on a Commonly Forgotten Stroke Mimic
Objective: Improve recognition of Diabetic Striatopathy (DS) as a stroke mimic causing acute hemichorea-hemiballismus, highlight factors leading to prolonged recovery, and propose tetrabenazine as a…Tourette – Like Phenotypes Following Combined Striatal Interneuron Loss.
Objective: To determine whether the ablation of Nkx2.1 derived striatal interneurons (SI) in mice produces Tourette-like phenotypes including abnormal movements and perseverative behaviors. Background: Tourette…A Post-mortem Study on Striatal Glia and Blood Brain Barrier Integrity in Aging and PD Asian-Indians.
Objective: We examined the glial and blood brain barrier (BBB) changes related to normal aging and PD in the Asian-Indian striatum. Background: increases the risk…GPR30 agonists attenuate haloperidol-induced neurotoxicity in SH-SY5Y cells and adult zebrafish.
Objective: Objective:1. To investigate the neuroprotective effect of FDA-approved compounds (Raloxifene and Fulvestrant) against haloperidol-induced neurotoxicity in SHSY-5Y cells and adult zebrafish2. To explore the molecular…Effects of ectopic dopamine D2 autoregulation of raphe-striatal projecting neurons on established L-DOPA-mediated behaviors in a hemiparkinsonian rat model
Objective: Levodopa (LD) is the standard treatment for Parkinson’s Disease (PD) despite risk of LD-induced dyskinesia (LID) development within a decade of treatment. Serotonergic (5-HT)…Higher Putamen Volume Asymmetry with Age-Preserved Volume in Isolated Adult-Onset Cervical Dystonia
Objective: This study aims to explore the relationship between left and right putamen volumes in cervical dystonia (CD) patients compared to age-matched healthy controls (HC),…The clinical features, neuroimagings and outcomes of diabetic striatopathy: a retrospective study at tertiary hospital in Vietnam
Objective: This study aims to analyze the clinical features, neuroimaging findings, and outcomes of diabetic striatopathy among Vietnamese patients. Background: Diabetic striatopathy (DS) is a…Diabetic striatopathy with stroke – like symptoms: A case report
Objective: To describe a rare case of diabetic striatopathy in a woman with type 2 diabetes mellitus presenting with unilateral hemichorea, dysarthria and left hemiparesis…Understanding diffusion in extracellular space in synucleinopathy
Objective: To understand the extracellular space (ECS) diffusion in synucleinopathy. Background: The pathogenic mechanisms underlying synucleinopathies involve the spread and propagation of α-synuclein aggregates throughout…
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