F1 crossbreds of C57BL/6 and CD-1 mice demonstrate resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced nigral neurodegeneration
Objective: To establish the neural basis of varying susceptibility to MPTP in MPTP resistant CD-1 mice, susceptible C57BL/6 mice and their crossbreds; simulating the variable…Dorsolateral nigral hyperintensity on 3.0 tesla susceptibility-weighted imaging in idiopathic rapid eye movement sleep behaviour disorder
Objective: To assess the loss of dorsolateral nigral hypersensitivity (DNH), which seems to correspond to nigrosome-1, using susceptibility-weighted imaging (SWI) at 3.0 Tesla (T) in…Magnetic resonance imaging of nigrosome-1 in the diagnosis of early Parkinson’s: Initial results of the Parkinson’s magnetic imaging repository (PaMIR)
Objective: To evaluate the accuracy of T2* weighted high resolution 3T Magnetic Resonance Imaging (MRI) in the diagnosis of Parkinson's disease (PD) in a prospective…Ultra high field magnetic resonance imaging of nigrosome 1 is a biomarker of new onset and premotor Parkinson’s disease
Objective: An unmet need exists to develop a methodology to diagnose Parkinson's disease (PD) in the premotor stage, so that patients can be enrolled in…Neuromelanin-MRI of substantia nigra subregions in Parkinson’s disease
Objective: To detect changes in the different subregions of the substantia nigra pars compacta (SNc) in patients with Parkinson's disease (PD) and to correlate the…
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