The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…Inter-Electrode Distance Influences the Spectral Power of Subthalamic Bipolar Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to evaluate spectral dissimilarities and their correlations with clinical symptoms of intra-operative local field potentials (LFP) acquired from wide- and close-spaced…Visualization Tool for DBS Programming with a Multiple Source, Constant Current System Reduces Initial Programming Time
Objective: We describe utilization of newly available visualization software for use as a Deep Brain Stimulation (DBS) planning tool during initial programming of patients with…LFP spectral features associated with therapy complications in typical and early onset Parkinson’s disease
Objective: The aim of this study was to search for potential markers in the subthalamic nucleus activity of parkinsonian patients associated with levodopa-induced dyskinesias in…Bilateral double beta peaks in a PD patient with STN electrodes
Objective: We aimed to record LFPs of the subthalamic nucleus (STN) from a PD patient with a new implantable pulse generator (IPG), which is capable…Focused ultrasound subthalamotomy in Parkinson’s disease: Lesion topography and improvement in cardinal motor features
Objective: To describe the topography of unilateral subthalamic nucleus (STN) lesions performed by magnetic-resonance guided focused ultrasound (MRgFUS) in Parkinson’s disease (PD), and define correlations…Effectiveness of lead position with microelectrode recording based support vector machine for characterizing the sub-cortical-structures via deep brain stimulus in Parkinson`s disease
Objective: To develop artificial intelligence(AI) machine/deep learning techniques for processing/analyzing MER signals of STN which will help the surgical-team (neurologists,neurosurgeons) for deciding optimal location of…Use of a new Stimulation Field Visualization Tool in Parkinson’s Disease Subjects Treated with Subthalamic Nucleus Deep Brain Stimulation (sub-analysis from INTREPID RCT)
Objective: To describe the location of stimulation fields as applied to optimized programming parameters in a cohort of STN DBS PD patients participating in INTREPID…Neural activity in the subthalamic nucleus in association with reward/loss processing in patients with Parkinson’s disease
Objective: To elucidate the electrophysiological correlates of the reward and loss processing during incentive anticipation and feedback in the subthalamic nucleus (STN) of patients with…Intraoperative test objectively for discovering optimal electrode site for effective imaging (by eye) and bilateral STN-DBS stereotactic functional neurosurgery
Objective: To convolve the subject-specific (SS) electric-stimulus-field (ESF) with tremor-progress and progression quantified through accelerometer and stimulus-induced adverse side-effects (SIASE), exhibit visually (by eye) in…
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