An Objective Tool to Guide Target Selection for DBS in PD (GPi vs STN)- integration into Thomas Jefferson’s multidisciplinary Movement Disorders Center, an Update
Objective: After the creation of a tool to aid in target selection for deep brain stimulation (DBS) in Parkinson’s disease (PD), our goal is to…Differential Effect of Dorsal and Ventral STN Stimulation on Perseveration and Evidence Accumulation
Objective: To study the differential effects of dorsal and ventral Subthalamic nucleus (STN) stimulation on perseveration and evidence accumulation in patients with Parkinson's disease (PD).…First Case of Tongue Twisting During Screening of STN DBS for Parkinson’s Disease: A Unique form of Pyramidal Tract Activation
Objective: STN-DBS is an effective,generally well-tolerated therapy in selected patients experiencing motor fluctuations,dyskinesia,resistant tremor despite oral/transdermal treatment. Side-effects can occur due to spread of electrical…Stimulation parameters of subthalamic deep brain stimulation in dystonia: a systematic review
Objective: To systematically analyze the stimulation parameters of the subthalamic nucleus (STN) deep brain stimulation (DBS) in patients with dystonia. Background: DBS is widely used…Outcomes of a Prospective, Multicenter, International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: Here we report the collected outcomes from a large-scale registry of a deep brain stimulation (DBS) system capable of Multiple Independent Current Source Control…Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
Objective: We test the hypothesis of modulating subthalamic neuronal firing pattern via injection of hyperpolarizing current as an effective treatment for hyperkinetic movement disorders. Background:…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: In this report, initial real-world outcomes using a directional lead with a deep brain stimulation (DBS) system capable of multiple independent current source control…Quantitative Susceptibility Mapping may help distinguish patients with Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy with predominant parkinsonism
Objective: The purpose of this study was to examine quantitative susceptibility mapping (QSM) changes in PD and multiple system atrophy with predominant parkinsonism (MSA-P) and…Directional versus conventional subthalamic deep brain stimulation for advanced Parkinson’s disease: Short-term outcomes of a pilot study
Objective: To investigate efficacy of STN-DBS via segmented directional leads compared to conventional omnidirectional leads in PD-patients. Background: Recently, novel leads which allow stimulation steering in…Increased attention for food stimuli as a mechanism for weight gain in patients with Parkinson’s disease undergoing DBS of the subthalamic nucleus
Objective: The purpose of this study was to investigate effects of STN DBS on food cue viewing and neural processing of food stimuli in PD…
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