DBS Withdrawal Syndrome in Advanced Parkinson’s Disease: A Case Series
Objective: Deep Brain Stimulation (DBS) is a widely used neuromodulation therapy for managing motor complications in advanced Parkinson’s disease (PD). However, abrupt cessation of DBS,…Cognitive Load Modulates Excitability of Subthalamic Motor Circuitry in Parkinson’s Disease
Objective: To characterize the effect of cognitive load on the excitability of circuitry connected with the subthalamic nucleus (STN) motor territory in Parkinson’s disease (PD)…Efficacy of Unilateral Focused Ultrasound Subthalamotomy in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy of unilateral focused ultrasound subthalamotomy (FUS-STN) in treating patients with Parkinson’s Disease (PD). Background: PD is a neurodegenerative disorder with…Single- and Multi-Unit Activity in STN Provides Enhanced Insight into Speech-Related Neural Dynamics in Parkinson’s Patients
Objective: We aimed to elucidate neural representations in local field potentials (LFP) and single- and multi-unit activity of subthalamic nucleus (STN) neurons during speech tasks,…Evoked Resonant Neural Activity localises STN DBS programs more ventrally than clinician and imaging-guided methods in Parkinson’s disease
Objective: To compare 3 methods of localising STN DBS programs for PD; 1) clinical standard of care (SOC), 2) imaging-based programming (IBP), 3) novel algorithm…Mapping aggregate monopolar sensing data of beta power local field potentials onto a common subthalamic nucleus in Parkinson’s disease patients
Objective: Compare local field potential (LFP) magnitude and anatomical location measured from a chronically implanted deep brain stimulation (DBS) lead within the subthalamic nucleus (STN)…Broad spectrum local field potential activities as a novel biomarker for adaptive deep brain stimulation
Objective: This study aims to evaluate the wider frequency range (1-200 Hz) LFPs as the novel neural biomarkers for adaptive DBS. In parkinsonism rats, we…Characterization of DBS-induced Speech Improvements in a German PD Cohort
Objective: To investigate speech changes induced by subthalamic deep brain stimulation (DBS) in persons with Parkinson’s disease (pwPD). Background: Dysarthria is a common debilitating motor…Approaches to understanding the role of STN in the development of ICD in Parkinson’s disease
Objective: The aim of this study was to identify the features of subthalamic tracts in PD patients with ICD. Background: Recurrent negative feedback loops from…Subthalamic versus Pallidal Temporal Interference Stimulation in Parkinson’s Disease: A Pilot Study
Objective: To investigate whether transcranial temporal interference stimulation (tTIS) targeting different deep brain regions produces symptom-specific improvements consistent with established deep brain stimulation (DBS) outcomes…
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