Levodopa/carbidopa intestinal gel treatment in advanced Parkinson’s disease: A long-term observational study
Objective: To evaluate long-term efficacy, levodopa dose changes and complications in patients with advanced Parkinson's disease (PD) treated. Background: Administrated via percutaneous gastric gastrostomy to…Is Apple Watch a new hope for patients with Parkinson’s disease?
Objective: To assess the capability of the smart watch (Apple Watch®) as a simple monitoring tool of motor fluctuation in patients with Parkinson's disease (PD).…Regional differences in the results of a phase 2b study of tozadenant in Parkinson’s disease patients with motor fluctuations
Objective: To assess how the efficacy of tozadenant differed by region in a randomized, double-blind, placebo-controlled trial of Parkinson's disease patients with motor fluctuations. Background:…Activities of daily living and motor scores of the UPDRS in fluctuating Parkinson’s disease patients treated with opicapone
Objective: Evaluate the effects of opicapone (OPC) on the activities of daily living and motor scores of the UPDRS in fluctuating Parkinson's disease patients. Background:…Real-life data on the use of levodopa carbidopa intestinal gel in Parkinson’s disease
Objective: To report our institution's initial clinical experience with initiation and management of levodopa carbidopa intestinal gel (LCIG) formulation Duopa®. Background: Carbidopa/levodopa intestinal gel (LCIG)…Exploratory efficacy of opicapone in fluctuating Parkinson’s disease patients at different stages of symptom progression
Objective: Evaluate the efficacy of opicapone (OPC) in fluctuating Parkinson's disease patients at different stages of symptom progression over a 14-15 week treatment period. Background:…Self-perception of daily performance in relation to motor performance in advanced Parkinson’s disease – Case studies
Objective: To evaluate Parkinson's disease (PD) patients' perception of their performance of daily living (ADL) in their “ON” and “OF” stages and relate them to…Evaluation of impulse control disorders in fluctuating Parkinson’s disease patients under opicapone treatment
Objective: Evaluate the impulse control disorders reported as adverse events in phase III studies with opicapone (OPC) in fluctuating Parkinson's disease patients. Background: Impulse control…Risk factors of wearing-off phenomenon in Parkinson’s disease in Japan
Objective: Parkinson's disease (PD) is one of common progressive neurodegenerative disorder involving nigrostriatal dopaminergic neurons. The aim of this study was to investigate risk factors…Onset and stabilization of opicapone treatment effects in fluctuating Parkinson’s disease patients: Exploratory by-week efficacy analysis of pooled phase III studies
Objective: Evaluate the onset and stability of the therapeutic effect of opicapone (OPC) compared to placebo in patients with Parkinson's disease and motor fluctuations over…