Objective: To investigate demography of sensory tricks in cervical dystonia, to discuss relationship between sensory tricks and function of sensorimotor integration in supplementary motor area of cortex, to explore potential worthiness using sensory tricks.

Background: Cervical dystonia is the most common type of focal dystonia. A puzzling feature of the disorder is phenomenon commonly known as “sensory tricks” or “geste antagonistes”. We investigated incidence of sensory tricks in patients with CD, and tried to explore the clinical correlation aiming at diagnosing the disease earlier and conducting appropriate therapy.

Methods: 1. Questionnaire on sensory tricks: to investigate the sensory tricks first recognized by 75 patients retrospectively，and performance when first admitted outpatient clinic.

2. Median nerve somatosensory evoked potential via Multipoint recording was measured in patients and controls, noting bilateral amplitudes of P22/N30 derived from F（3,4）.

3. Tsui score noted.

Results: 1. The frequency of sensory tricks in CD is 85.53%. As disease progressed, type of sensory tricks may transform or even disappear.

2. No significant differences are found among ages of patients using classic sensory tricks, forcible tricks and patients without sensory tricks, whereas the complexity of the disease shows increased tendency among the there groups.

3. Bilateral P22/N30 amplitudes of patients with classic sensory tricks appear no significant differences (P>0.05). P22/N30 amplitudes contralateral to the head turn is significantly higher than ipsilateral in patients using forcible tricks and patients without sensory tricks (P<0.05) .

4. Tsui scores among patients using classic sensory tricks and forcible tricks or patients without sensory tricks appear significant differences (P<0.05), whereas scores between patients using forcible tricks and patients without sensory tricks appear no significant differences (P>0.05). Before and one month after focal injection of botulinum toxin type A therapy, changes of Tsui scores appear no significant difference among there groups.

Conclusions: 1. Types of sensory tricks using by patients are associated with severity of the disease;

2. Different types of sensory tricks may reflect status of adaptive compensatory mechanism of the cortex;

3. Focal injection of botulinum toxin type A therapy is an effective management regardless of patients using different types of sensory tricks.

References: [1] Kagi G, Katschnig P, Fiorio M, Tinazzi M, Ruge D, Rothwell J, et al. Sensory tricks in primary cervical dystonia depend on visuotactile temporal discrimination. Mov Disord 2013;28:356-61.

[2] Loyola DP, Camargos S, Maia D, Cardoso F. Sensory tricks in focal dystonia and hemifacial spasm. Eur J Neurol 2013;20:704-7.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/research-on-relationship-between-sensory-tricks-of-cervical-dystonia-and-function-of-cerebral-cortex/