Objective: Determine benefits of vestibular rehabilitation involving virtual reality through the comparison of pre-intervention and post-intervention evaluations in individuals with hereditary spastic paraplegia.
Background: Neurodegenerative diseases are sporadic hereditary conditions characterized by progressive dysfunction of the nervous system. Such conditions are generally associated with atrophy of the affected structures of the central or peripheral nervous system. Among the multiple symptoms, vestibulopathy is one of the causes of discomfort and the loss of quality of life. Hereditary spastic paraplegia (HSP) is a heterogenous group of hereditary degenerative diseases involving the disorder of a single gene and is characterized by the progressive retrograde degeneration of long axonal fibers of the corticospinal tracts of the spinal cord.
Method: Research approved on the Rebec platform trials RBR-3JMX67, it is a randomized controlled study, with hidden allocation and blinded evaluator. Participants: 40 patients diagnosed with hereditary spastic paraplegia. Interventions: Patients eligible for this study underwent assessment protocols at the beginning and after the intervention. Group I: Twenty volunteers will undergo vestibular rehabilitation with virtual reality (balance games) using the Wii® console, the Wii-Remote and the Wii Balance Board (Nintendo). The games last from 30 minutes to an hour, with sessions twice a week for 10 weeks (total: 20 sessions). Group II: Twenty volunteers will undergo vestibular rehabilitation with virtual reality (balance games and muscle strength games) using the Wii® console, the Wii-Remote and the Wii Balance Board (Nintendo). The games last from 30 minutes to an hour, with sessions twice a week for 10 weeks (total: 20 sessions).
Results: Provide a assessment of the effectiveness and cost-effectiveness of a virtual reality vestibular rehabilitation program to reduce the progressive effects of the disease by providing an affordable and affordable differentiated treatment perspective.
Conclusion: The study will provide a assessment of the efficacy and cost-benefit of a vestibular rehabilitation program with the Nintendo Wii® involving virtual reality to reduce the progressive effect of the disease, offering a different treatment option, additional to other conventional methods, accessible and low cost.
To cite this abstract in AMA style:
B. Zeigelboim, G. Santos, M.I Severiano, H. Teive, B. Cavalcante-Leao. Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial [abstract]. Mov Disord. 2020; 35 (suppl 1). https://www.mdsabstracts.org/abstract/balance-rehabilitation-with-a-virtual-reality-protocol-for-patients-with-hereditary-spastic-paraplegia-protocol-for-a-clinical-trial/. Accessed June 15, 2025.« Back to MDS Virtual Congress 2020
MDS Abstracts - https://www.mdsabstracts.org/abstract/balance-rehabilitation-with-a-virtual-reality-protocol-for-patients-with-hereditary-spastic-paraplegia-protocol-for-a-clinical-trial/