Objective: We aim to evaluate the prevalence of depression in disorders including multiple sclerosis (MS), Parkinson’s disease (PD), migraine, and stroke. Also, we detect risk factors for depression occurrence within each disorder. Moreover, we compare the risk factors in these four common Neurologic disorders.
Background: Depression is a globally prevalent Psychologic disorder and common morbidity in chronic conditions such as neurological diseases. Although depression correlates with neurological disorders, it is mostly underdiagnosed in chronic patients and causes numerous adverse effects.
Method: We designed a cross-sectional study and used the database of neurology specialty clinics in a hospital in Tehran, the largest city of Iran. Five hundred twenty patients, including 105 PD patients, 101 patients with stroke, 213 cases with MS, and 100 Migraine patients, were assessed. They were asked about their chief characteristics and disease-specific variables that may cause depression. Moreover, depression criteria were measured with three internationally used scales.
Results: Overall, the prevalence of depression in PD, stroke, MS, and migraine, according to the Beck Depression Inventory (BDI-II), were 43.8%, 38.6%,45.1%, and 37.6%, and according to The Hamilton Depression Rating Scale (HDRS) scale, were 56.2%, 51.5%, 39.4%, 43.6% respectively. Finally, according to the Diagnostic and Statistical Manual of Mental Disorders Self-Rated Level 1 Cross-Cutting Symptom Measure—Adult (DSM XC) the depression prevalence were 64.8%, 34.7%, 36.2%, and 67.3% respectively. Possible risk factors of depression were lower educational level, disease severity, socioeconomic level, marital or employment status, female gender, higher age, and consumption of some specific drugs.
Conclusion: Depression is a widespread disorder in chronic neurologic conditions. Our data suggests the odds of depression in neurologic disorders depend on the characteristics of the patient and the features of the disease.
To cite this abstract in AMA style:
F. Hojjati Pour, M. Salari, H. Pakdaman, M. Etemadifar, N. Mirjamali, M. Khalkhali, A. Farahani. Risk of Depression after Parkinson’s disease, stroke, multiple sclerosis, and migraine in an Iranian population [abstract]. Mov Disord. 2023; 38 (suppl 1). https://www.mdsabstracts.org/abstract/risk-of-depression-after-parkinsons-disease-stroke-multiple-sclerosis-and-migraine-in-an-iranian-population/. Accessed June 15, 2025.« Back to 2023 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/risk-of-depression-after-parkinsons-disease-stroke-multiple-sclerosis-and-migraine-in-an-iranian-population/