Category: Telemedicine
Objective: To evaluate the feasibility of a smartphone-based platform for remote patient-reported outcome (PRO) collection in Parkinson’s disease (PD) and explore its utility in identifying clinical characteristics (i.e., sex differences) in real-world settings.
Background: Mobile health (mHealth) platforms offer transformative advantages for PD real-world research, including real-time symptom tracking, reduced geographic barriers, and continuous patient engagement. However, the feasibility of such platforms in PD populations remains understudied.
Method: We have previously developed ‘PaWei’, a PD management smartphone app. with more than 15,000 users from 126 hospitals in mainland China. The app. has been listed in Movement Disorder Society (MDS) Digital App Repository. The platform enabled remote self-reporting of motor/non-motor symptoms, quality of life, and medication via questionnaires and validated rating scales. Data of 1,828 validated PD patients (1,001 male, 827 female) were analyzed to explore sex differences in self-reported clinical characteristics.
Results: The platform demonstrated robust feasibility in collecting data from geographically diverse PD patients across mainland China, including older adults with a mean age of 61 years. Secure data transmission and storage were maintained throughout the study. Secondary sex-based analyses identified notable disparities, such as a higher prevalence (p<0.001) of depression among females.
Conclusion: This study validates the feasibility of a smartphone-based platform for large-scale PRO collection in PD, offering a scalable solution for PD real-world research. Sex differences in clinical characteristics were identified based on app. data. The platform’s success in real-world settings underscores its potential to support longitudinal monitoring, personalized interventions, and inclusive research, particularly in underserved regions.
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To cite this abstract in AMA style:
Z. Xu, Y. Tang, J. Wang. Leveraging a Smartphone-based Platform for Parkinson’s disease Real-world Research: A Multicenter, Cross-sectional Feasibility Assessment Study [abstract]. Mov Disord. 2025; 40 (suppl 1). https://www.mdsabstracts.org/abstract/leveraging-a-smartphone-based-platform-for-parkinsons-disease-real-world-research-a-multicenter-cross-sectional-feasibility-assessment-study/. Accessed November 20, 2025.« Back to 2025 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/leveraging-a-smartphone-based-platform-for-parkinsons-disease-real-world-research-a-multicenter-cross-sectional-feasibility-assessment-study/