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Effectiveness of Interactive Rhythmic Stimulation on Gait Improvement in Elderly Patients: An R and Python Perspective

N. Ali, Z. Hegazy, K. Ahmed, O. Sabry, S. Elsenbawy, G. Abozeid, D. W. Ismail, H. Elshazly, Y. M.HUSSEINY, S. Elrobeigi, Y. Hamdi, M. Abouelseoud, H. Abdelbar, H. Khabiry, M. M. Elsayed (Mansoura, Egypt)

Meeting: 2025 International Congress

Keywords: Parkinson’s

Category: Technology

Objective: To evaluate the effectiveness of interactive rhythmic stimulation on gait improvement in elderly patients using data-driven insights from R and Python-based analyses.

Background: Gait deterioration is a major contributor to falls and mobility impairment in aging populations. Interactive rhythmic stimulation (IRS), incorporating auditory, visual, and tactile cues, has shown promise in enhancing gait patterns and stability. However, the effectiveness of IRS interventions remains inconsistent across studies. Utilizing R and Python, advanced statistical and machine learning techniques can provide robust insights into the impact of rhythmic stimulation on gait parameters and functional mobility.

Method: A systematic review of randomized controlled trials (RCTs) and observational studies was conducted using PubMed, Scopus, Web of Science, and IEEE Xplore databases up to March 2024. Inclusion criteria encompassed studies assessing IRS interventions for gait improvement in elderly patients (>60 years). Extracted data included stimulation modality, intervention duration, gait parameters (cadence, stride length, step variability), and functional outcomes. R-based mixed-effects models and Python-driven machine learning techniques were applied to analyze trends and predictive factors influencing gait improvement.

Results: A total of 29 studies (n = 1,180 participants) met inclusion criteria. Meta-analysis revealed that IRS significantly improved gait velocity (Hedges’ g = 0.82, p < 0.001) and stride length (Hedges’ g = 0.76, p = 0.002). Python-based machine learning models identified auditory stimulation as the most effective cue, enhancing step synchronization by 32%. R-based statistical modeling confirmed that rhythmic stimulation reduced step-time variability in Parkinson’s patients by 27%. Subgroup analysis indicated that multimodal rhythmic stimulation produced superior results compared to unimodal interventions.

Conclusion: Interactive rhythmic stimulation is an effective intervention for gait improvement in elderly patients, with auditory cues demonstrating the most significant impact. The integration of R and Python for statistical and machine learning analyses enhances the understanding of gait adaptations, supporting personalized rehabilitation strategies. Future research should focus on real-time adaptive rhythmic stimulation models to further optimize gait training outcomes.

To cite this abstract in AMA style:

N. Ali, Z. Hegazy, K. Ahmed, O. Sabry, S. Elsenbawy, G. Abozeid, D. W. Ismail, H. Elshazly, Y. M.HUSSEINY, S. Elrobeigi, Y. Hamdi, M. Abouelseoud, H. Abdelbar, H. Khabiry, M. M. Elsayed. Effectiveness of Interactive Rhythmic Stimulation on Gait Improvement in Elderly Patients: An R and Python Perspective [abstract]. Mov Disord. 2025; 40 (suppl 1). https://www.mdsabstracts.org/abstract/effectiveness-of-interactive-rhythmic-stimulation-on-gait-improvement-in-elderly-patients-an-r-and-python-perspective/. Accessed October 5, 2025.
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