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Time perception patterns in patients with Parkinson’s disease and Alzheimer’s disease

A. Chimagomedova, O. Levin (Moscow, Russian Federation)

Meeting: 2025 International Congress

Keywords: Cognitive dysfunction

Category: Parkinson's Disease: Cognition / Psychiatric Manifestations / Lewy Body Dementia

Objective: We conducted this study to assess different patterns of time perception in patients with Parkinson’s disease (PD) and Alzheimer’s disease (AD).

Background: Time perception is one of the most important functions of the brain. Temporal discrimination is a necessary ability in everyday activities and partially is perceived through the participation of cognitive functions and emotional state. It’s known that time perception undergoes significant pathological changes in patients with neurodegenerative diseases.

Method: We have been examining 28 patients with PD (14 right-onset and 14 left-onset) and 22 patients with AD. All the patients underwent examination on MoCA, MMSE, The Apathy Scale, Plutchik’s Impulsivity Scale. We used tests to assess implicit and explicit time perception. The implicit time perception tests included: 1) video test where patient should determine the duration of symbol appearance, 2) question after 20 minutes of entering room how long time passed from the beginning to now. The explicit test was a test with a stopwatch indicating intervals of 5 seconds 4 times. Parkinsonism severity in patients with PD was assessed with UPDRS part III.

Results: In PD patients, there was a tendency toward changes in both implicit and explicit time perception, in the absence of other cognitive impairments, impulsive disorders, and regardless of the severity of motor disturbances. Patients with right-onset had worse results in time perception tests compared to left-sided patients (p<0,05). In AD patients, implicit time perception was more impaired, in both test of 20 minutes and video-test.  It was highly associated with cognitive impairment (p<0,05).

Conclusion: Our findings suggest different time perception patterns in patients with PD and AD. Further investigation in this field is needed to detail the characteristics and pathoanatomy of these disturbances and the potential role in cognitive rehabilitation.

To cite this abstract in AMA style:

A. Chimagomedova, O. Levin. Time perception patterns in patients with Parkinson’s disease and Alzheimer’s disease [abstract]. Mov Disord. 2025; 40 (suppl 1). https://www.mdsabstracts.org/abstract/time-perception-patterns-in-patients-with-parkinsons-disease-and-alzheimers-disease/. Accessed October 5, 2025.
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