Objective: To study the effect of disease duration , age of the patient, MOCA on neuropsychiatric manifestations in Fifty PD patients.

Background: Neuro psychiatric symptoms including depression, anxiety, apathy and psychosis are common in Parkinson disease affecting majority of patients at some time in disease course. These have important consequences for quality of life and daily functioning.

Method: Fifty consecutive Parkinson patients diagnosed based on clinical manifestations as per UK Brain bank criteria were included. SAPS score (Scale for Assessment of Positive symptoms) was done in all patients.SAPS is split into 4 domains and within each domain separate symptoms are rated from 0 (absent) to 5(severe). SAPS includes Hallucinations, Delusions, Bizarre Behaviour, Positive Formal Thought Disorder. MOCA for cognitive assessment and other parameters like disease duration, age, pre and post-operative (DBS) status were noted. We did a correlation coefficient for SAP score and MOCA, disease duration, age of the patient.

Results: We found no correlation between SAPS & Disease duration, age of the patient, MOCA. P value between SAPS & disease duration is 0.59, P value between SAPS & age of the patient is 0.33, P value between SAPS & MOCA is 0.27 which are not significant.

Conclusion: Psychiatric abnormalities are common in PD. We found no correlation between age, disease duration, cognition with SAP Score.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/a-study-of-factors-causing-psychiatric-abnomalities-in-patients-with-parkinsons-disease/