Category: Parkinsonism, Atypical: MSA
Objective: To provide short, high-quality videos and MRI images presenting typical MSA features to supplement new MDS-MSA criteria1.
Background: The MDS criteria for the diagnosis of MSA have been published in 2022 to optimize diagnostic sensitivity and specificity. Used in a correct and clinically precise way, the new criteria support the diagnosis in early disease stages, but symptoms and MRI scans must be interpreted correctly.
Method: Prior to video recording, all participants provided a written informed consent for recording and publishing their videos/images. The collected recordings had to highlight a specific clinical or imaging feature in high-quality resolution. Where necessary, body parts were blurred or descriptions added to the videos. All videos were uploaded to a dedicated server and the most educational ones were selected in a structured consensus process.
Results: Out of 93 videos and 28 images collected, a total of 35 videos and 8 images were selected for the publication. Videos/images present core clinical features, supportive motor and non-motor features and MRI features following the operationalized definitions given in the lexicon of the MDS-MSA diagnostic criteria. Two cases of possible prodromal MSA were chosen to represent progression from pure autonomic failure to clinically established MSA. Where necessary, symptom description or timeframe of examination was added within the video as subtext.
Conclusion: The MSA videolibrary visually demonstrates clinical and imaging features to support clinicians in diagnosing MSA more accurately.
References: 1. Wenning GK, Stankovic I, Vignatelli L, et al. The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy. Mov Disord. Jun 2022;37(6):1131-1148. doi:10.1002/mds.29005
To cite this abstract in AMA style:
V. Sidoroff, A. Antonini, A. Batla, N. Bendahan, G. Calandra Buonaura, N. Campese, G. da Prat, M. Fabbri, A. Fanciulli, J. Ferreira, F. Gandor, D. Goldstein, T. Gurevich, S. Katzdobler, H. Kaufmann, J. Klempir, V. Kostic, F. Krismer, V. Khurana, A. Lang, J. Levin, N. Mcfarland, P. Millar Vernetti, M. Pellecchia, I. Petrovic, W. Poewe, N. Quinn, C. Raccagni, R. Moiron Simões, W. Singer, M. Michael Strupp, M. Stamelou, G. Höglinger, G. Wenning, I. Stankovic. Increasing diagnostic accuracy of Multiple System Atrophy – A Videolibrary on clinical and imaging features [abstract]. Mov Disord. 2024; 39 (suppl 1). https://www.mdsabstracts.org/abstract/increasing-diagnostic-accuracy-of-multiple-system-atrophy-a-videolibrary-on-clinical-and-imaging-features/. Accessed June 15, 2025.« Back to 2024 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/increasing-diagnostic-accuracy-of-multiple-system-atrophy-a-videolibrary-on-clinical-and-imaging-features/