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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2024 International Congress » Parkinsonism, Atypical: MSA

Meeting: 2024 International Congress

A 3D CNN Approach for the Classification of Multiple System Atrophy using Multimodal Multicentric MRI

GM. Mattia, L. Chougar, WG. Meissner, A. Foubert-Samier, A. Pavy-Le Traon, O. Rascol, M. Fabbri, S. Lehéricy, P. Péran (Toulouse, France)

A Phase 2 Study of ATH434 a Novel Inhibitor of α-Synuclein Aggregation for the Treatment of Multiple System Atrophy

D. Stamler, C. Wong, P. Trujillo, M. Bradbury, C. Lucas, D. Claassen (Newark, USA)

Altered activity of lysosomal hydrolases in monocyte-derived macrophages as potential biomarker for differential diagnosis of multiple system atrophy

K. Basharova, A. Bezrukova, G. Baydakova, I. Miliukhina, E. Zakharova, S. Pchelina, T. Usenko (Gatchina, Russian Federation)

Association Between Clinical Progression in Multiple System Atrophy and Brain Volume Changes Evaluated via Deep Learning Segmentation

D. Claassen, K. Hett, A. Brown, A. Wynn, C. Wallace, K. Rose, M. Bradbury, C. Wong, D. Stamler, P. Trujillo (Nashville, USA)

Brain De-Ironization with Nasal Spray of Iron Chelator in Treatment of Multiple System Atrophy, a Case Trial

A. Amoushahi, A. Sahebkar, P. Moeini, N. Chitsaz (Isfahan, Islamic Republic of Iran)

Catalan MSA Registry (CMSAR): Applying new Clinical Criteria and Biomarkers for Increasing Diagnostic Accuracy, is New Better?

A. Pérez-Soriano, C. Painous, J. Pérez, M. Fernandez, Y. Compta, Consortium, MJ. Martí (Barcelona, Spain)

Characteristics of Language Abnormalities in Multiple System Atrophy and Parkinson’s Disease

M. Subert, M. Novotny, P. Dusek, J. Klempir, J. Rusz, T. Tykalova (Prague, Czech Republic)

Clinical and neuroimaging factors associated with survival in Multiple System Atrophy

G. Martí-Andrés, E. Prieto-Azcárate, CA. Espinoza-Vinces, M. Riverol, J. Arbizu, MR. Luquin-Puido (Pamplona, Spain)

Combining alpha-synuclein PET and seeded amplification assays to improve the diagnostic accuracy of Multiple System Atrophy of the Parkinsonian subtype (MSA-P)

D. Rodriguez Gomez, B. Changizi, C. Sandiego, A. Green, A. Kuzkina, J. Alexander, O. Laun, K. Jones, D. Ceku, J. Meehan, S. Perumalla, S. Rai, A. Knorr, V. Hliva, M. Kosco-Vilbois, A. Pfeifer, N. Mendonca, D. Russell, F. Capotosti, V. Khurana (Boston, USA)

Correlation of lmaging Markers with Clinical Features in Multiple System Atrophy Patients

N. Jin (Hangzhou, China)

Effect of rehabilitation therapy on the motor functions in patients with multiple system atrophy

J. Lee, S. Jo, M. Choi, SJ. Chung (Seoul, Republic of Korea)

Explore cellular heterogeneities of orbitofrontal cortex in multiple system atrophy using spatial transcriptomics

SY. Cheng, CL. Hsu, WH. Yu, KP. Chang, MC. Kuo (Taipei, Taiwan)

Familial Multiple System Atrophy-Mimics: Importance of Comprehensive Evaluation

CH. Jeong, HJ. Kim (Seoul, Republic of Korea)

Heterogeneity of multiple system atrophy with an analysis of the clinical case

M. Karzhaubayeva (Almaty, Kazakhstan)

Increasing diagnostic accuracy of Multiple System Atrophy – A Videolibrary on clinical and imaging features

V. Sidoroff, A. Antonini, A. Batla, N. Bendahan, G. Calandra Buonaura, N. Campese, G. da Prat, M. Fabbri, A. Fanciulli, J. Ferreira, F. Gandor, D. Goldstein, T. Gurevich, S. Katzdobler, H. Kaufmann, J. Klempir, V. Kostic, F. Krismer, V. Khurana, A. Lang, J. Levin, N. Mcfarland, P. Millar Vernetti, M. Pellecchia, I. Petrovic, W. Poewe, N. Quinn, C. Raccagni, R. Moiron Simões, W. Singer, M. Michael Strupp, M. Stamelou, G. Höglinger, G. Wenning, I. Stankovic (Innsbruck, Austria)

Intraepidermal Nerve Fiber Density at Baseline Associates with One-year Clinical Disease Progression in Multiple System Atrophy

M. Andréasson, P. Karlsson, K. Samuelsson, P. Svenningsson (Stockholm, Sweden)

Lyme disease presenting as a rapidly progressive MSA-C look alike

L. Zünd-Hofer, F. Brugger (Sankt Gallen, Switzerland)

Multifaceted Challenges in Multisystem Atrophy Management: Medication Sensitivity, Emotional Lability, and Increased Fall Risk

G. Legerme, B. Carr, C. Rowan (Gainesville, USA)

Multiple System Atrophy in a Patient with Normal Pressure Hydrocephalus

E. Hayden, M. Elkasaby, B. Appleby (Cleveland, USA)

Optical Coherence Tomography Findings in Multiple System Atrophy: Insights into Disease Subtypes, Clinical Correlations, and Dopaminergic Degeneration

Y. Kang (Hangzhou, China)

Pain types in multiple system atrophy: results from a community-based survey

N. Campese, G. Göbel, L. Kaltenbach, J. Wanschitz, A. Schlager, B. Caliò, F. Leys, P. Bower, L. Kellermann, L. Zamarian, K. Bannister, R. Chauhuri, A. Schrag, R. Freeman, H. Kaufmann, R. Granata, S. Kiechl, W. Poewe, K. Seppi, G. Wenning, A. Fanciulli (Innsbruck, Austria)

Pharmacokinetics And Safety Of YA-101, A Dual Inhibitors Of D-Amino Acid Oxidase (DAAO) And NLRP3 Inflammasome, In Healthy Subjects: A Double-Blind, Placebo-Controlled, Randomized, Single Dose and Multiple Dose Phase I Study

YJ. Tseng, BH. Su, O. Lin, DZ. Luo, TF. Lo, YC. Huang, CC. Li (Taipei, Taiwan)

Plasma MicroRNA Expression Profiling in patients with Multiple System Atrophy and Parkinson’s Disease

R. Yadav, P. Ramaswamy, PK. Pal, R. Christopher (Bengaluru, India)

Posterior Fossa Arachnoid Cysts In Two Patients With Suspected Multiple System Atrophy – Cerebellar Type

A. Blazek, E. Flanagan, E. Coon, L. Jackson (Rochester, USA)

Prevalence of autonomic symptoms in Multiple System Atrophy on the background of probable RBD

H. Karkourian, L. Atabekyan, N. Nadryan, E. Balian, A. Grigoryan, S. Khachatryan, Z. Tavadyan (Yerevan, Armenia)

Prognostic role of postganglionic cardiovascular dysfunction in Multiple System Atrophy

R. Telese, A. Elia, R. Cilia, F. Colucci, V. Leta, A. Braccia, L. Romito, R. Eleopra, G. Devigili (Milan, Italy)

Prospective Study of Gait and Multimodal MRI Biomarkers for Multiple System Atrophy

F. Marchand, R. Viard, D. Devos, L. Defebvre, T. Ollivier, D. Guehl, G. Kuchcinski, C. Moreau (LILLE, France)

Role of the Alpha-synuclein Seed Amplification Assay in Parkinson’s Disease Clinical Trials: A Case Report of Multiple System Atrophy Misdiagnosed as Parkinson’s Disease

E. Tharp, J. Martinez-Lemus, J. Suescun, C. Adams, M. Shahnawaz, T. Ellmore, M. Schiess (Houston, USA)

Safety and Efficacy of the Anti-alpha Synuclein Monoclonal Antibody Lu AF82422 for the Treatment of Patients with MSA: Results from the Phase 2 AMULET Trial

W. Singer, S. Zanigni, L. Kjærsgaard, J. Wiedemann, P. Kallunki, K. Kompus, M. Jørgensen, M. Flensburg, A. Bidani, JL. Molinuevo, A. Takeda, B. Grønning, J. Luthman (Rochester, USA)

Seed Amplification Assay for the differentiation of αSyn seed subtypes

C. Farris, S. Weber, Y. Ma, H. Nguyen, S. Rosete-Gonzalez, A. Siderowf, U. Kang, B. Mollenhauer, L. Concha-Marambio (san diego, USA)

Serotonin Transporter Dynamics in Multiple System Atrophy: Insights from 123I-FP-CIT SPECT Imaging

R. Nagao, H. Watanabe (Toyoake, Japan)

Syllable-based speech characteristics as potential biomarker for differential diagnosis of Parkinson’s disease, multiple system atrophy, and cerebellar ataxia

B. Jin, H. Kim, K. Woo, J. Shin (Seoul, Republic of Korea)

The Clinical Implication of Dysphagia in Patients with Multiple System Atrophy

MG. Choi, SY. Jo, JH. Lee, SJ. Chung (Seoul, Republic of Korea)

TOPAS-MSA: Targeting Oligomer Pathology of Alpha-Synuclein – A Study Evaluating the Safety and Efficacy of Emrusolmin in Patients with Multiple System Atrophy

J. Levin, T. Matthias, H. Knebel, S. Barash, L. Marinelli, A. Ahn, A. Giese, M. Chen, J. Nettleship ()

Treatment Patterns and Comorbidities Associated with Multiple System Atrophy: A Comparative Study

S. Kaplan, H. Xie, A. Kumar (Netanya, Israel)

Unsupervised Learning Approach for Pathology-Based Subtyping and Staging Multiple System Atrophy

H. Sekiya, D. Ono, D. Dickson (Jacksonville, USA)

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