Feasibility and Preliminary Outcomes of an Online Fatigue Self Management Programme for People With Parkinsons Disease
Objective: To assess the feasibility, acceptability, and preliminary outcomes of an online fatigue self management programme for people with Parkinsons disease. Background: Fatigue is a…Exploratory Results From a Phase 1 Study of NIO752 in Progressive Supranuclear Palsy Supporting Further Clinical Studies
Objective: To report exploratory analyses of biomarker and clinical outcomes from a first-in-human study of NIO752 in progressive supranuclear palsy (PSP) and provide rationale for…Developing a toolkit for the assessment and management of lower urinary tract symptoms in parkinsonism
Objective: To develop an easy to use toolkit that expedites the work-up and management of lower urinary tract symptoms (LUTS) in people with parkinsonism for…Assessment of α-Synuclein Seeding Activity in the Olfactory Mucosa after SARS-CoV-2: a Pilot Study
Objective: To determine whether symptomatic SARS-CoV-2 infection is associated with local α-synuclein (aSyn) aggregation in the olfactory mucosa (OM) as measured by an aSyn seeding…Assessment of GCA repeat expansion in the GLS gene among Indian patients with Spinocerebellar Ataxia
Objective: Spinocerebellar ataxia (SCA) is a group of neurodegenerative disorders. More than 40 microsatellite repeat loci have been associated with ataxia. The GCA repeat expansion…Beta and Gamma Local Field Potentials in Chronic Deep Brain Stimulation for Parkinson’s Disease: Programming Implications from a Systematic Review
Objective: To define distinct clinical roles of beta- and gamma-band local field potential (LFP) biomarkers in chronic deep brain stimulation (DBS) for Parkinson’s disease (PD)…Cross-Cultural Validation of the Hebrew version of The International Parkinson and Movement Disorder Society Non-Motor Rating Scale
Objective: This study aims to validate the Hebrew version of the MDS-NMS and make it suitable for use in Hebrew speaking population Background: Parkinson's disease is a complex neurodegenerative disease with…Suicidal Ideation and the Hippocampal Histaminergic System in Huntington’s Disease: A PET Study
Objective: To determine whether presence and severity of suicidal ideation (SI) are associated with hippocampal volume and histamine H3 receptor (H3R) PET uptake in people with Huntington’s disease (PwHD). Background: Suicidal ideation occurs in approximately 8–27% of PwHD, yet its causes remain unclear(1–3). The…Characterising immune changes in the nose in Parkinson’s disease
Objective: To characterise the profile of innate immune cells in the nasal cavity in people with Parkinson’s disease (PD) versus controls. Background: Neuroinflammation provides novel…Qihuang Needle Therapy for Motor Symptoms in Parkinson’s Disease: A Randomized Controlled Trial
Objective: To evaluate the efficacy of Qihuang needle therapy for improving motor and non-motor symptoms in patients with Parkinson’s disease (PD). Background: Motor symptoms in…
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