Efficacy of Novel Antipsychotic Agents on Cognitive Functions in Parkinson’s Disease: A Systematic Review and Meta-analysis of 2,533 Patients
Objective: To systematically evaluate and quantitatively synthesize evidence on the effects of novel antipsychotic agents (Clozapine, Olanzapine, Risperidone, and Aripiprazole) on cognitive domains in Parkinson’s…Perception of Early-Intervention Therapies and Clinically Meaningful Delays in Huntington’s Disease Onset and Progression: The Pre-HDBOI Study
Objective: To characterize willingness among people with premanifest Huntington’s disease (PwPHD) to consider early-intervention therapies if available, the minimally acceptable delay in HD onset/progression, and…Diagnosing Prodromal Synucleinopathies – What is the Role of Cardiac MIBG Scintigraphy?
Objective: We aimed to characterize cardiac MIBG uptake patterns in patients with an initial diagnosis of PAF (iPAF) and assess their role as a prognostic…Delineating Therapeutic and Non-therapeutic Neural Signatures of Deep Brain Stimulation
Objective: To develop an information-theoretic framework that identifies neural signatures predicting therapeutic benefit, independent of stimulation artifacts, enabling objective DBS parameter optimization. Background: DBS programming…Risk factors associated with Parkinson’s disease in the DRC (Case of the Initiative Plus Hospital Center, Kinshasa)
Objective: identify factors that could be associated with Parkinson's disease in Congo Background: In DRCongo, few studies have been published on Parkinson's disease to date.At…Digital Health, Telemedicine, and Artificial Intelligence in Parkinson’s Disease Management During COVID-19: A Narrative Review
Objective: The objective of this narrative review was to evaluate the effectiveness of telemedicine and AI-based technologies used for the remote monitoring and management of…Early Clinical Characteristics of Pathologically Confirmed Progressive Supranuclear Palsy and Corticobasal Degeneration
Objective: This study aimed to characterize the early clinical features of PSP and CBD to inform clinicians on diagnostic assessment and management strategies. Background: Although…A Real World Case Series of the Nidra Transcutaneous Afferent Patterned Stimulation Device in Moderate-to-Refractory Restless Legs Syndrome
Objective: To describe real-world use, tolerability, and clinical response to Nidra transcutaneous afferent patterned stimulation device in moderate-to-refractory restless legs syndrome (RLS). Background: RLS can…Military-related associations with Parkinson’s disease (PD) in the Millenium Cohort Study
Objective: To examine associations between military-related exposures and PD. Background: The Millennium Cohort Study is a large prospective cohort of 260,228 US service members and…A prospective single-center study investigating the utility of supportive features in the diagnosis of multiple system atrophy with predominant cerebellar ataxia
Objective: The present study aimed to determine the utility of supportive motor and nonmotor features in differentiating multiple system atrophy (MSA) with predomainat cerebellar ataxia…
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