Effect of Levodopa-Carbidopa Intestinal Gel Versus Optimized Medical Treatment on Dyskinesia in Advanced Parkinson’s Disease Patients: Final Results of the Randomized 12-Week DYSCOVER Study
Objective: This study evaluated the effectiveness of LCIG versus optimized medical treatment (OMT) on the duration and severity of dyskinesia in aPD patients. Background: Approximately…Determination of non-motor symptoms in Parkinson’s disease in Kazakhstan (on the example of the city of Almaty)
Objective: To identify non-motor symptoms in patients with Parkinson's disease, depending on the severity of the disease. Background: Parkinson's disease is a chronic disease, as…Severity of Motor Symptoms in Parkinson’s Disease in Kazakhstan (on the example of the city of Almaty)
Objective: Determine the severity of motor symptoms with Parkinson's disease using the MDS-UPDRS scale. Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by…Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study
Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: A real-life study
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea (10 injection cycles into the…Population pharmacokinetic analysis of levodopa and carbidopa after subcutaneous administration with and without adjunct oral therapy
Objective: To develop population pharmacokinetic (PK) models for levodopa (LD) and carbidopa (CD) following subcutaneous (SC) infusion, including adjunct oral LD/CD administration. Background: ND0612 is…The Personalized Parkinson Project – data quality enhancing strategies
Objective: Demonstrate the impact of quality enhancing strategies in the Personalized Parkinson Project. Background: Increasingly, the scientific community uses data from longitudinal observational patient cohorts…Phase I-II first-in-human clinical trial of intraputamenal CDNF in Parkinson’s disease: Topline results of the six-month double-blind placebo-controlled main study and the six-month active treatment extension study
Objective: To assess the safety and tolerability and to explore the preliminary efficacy of intermittent intraputamenal monthly infusions of CDNF in subjects with advanced idiopathic…Using mindfulness to improve self-awareness in Parkinson’s disease patients – preliminary results of a randomized controlled trial
Objective: This clinical trial aims to investigate the effects and feasibility of a newly developed 8-week mindfulness intervention on self-awareness in Parkinson’s disease (PD) patients.…Effect of Combined Modality Treatment on Sustained Phonation in Parkinson’s Disease
Objective: To determine whether Lee Silverman Voice Treatment (LSVT-LOUD(R)) combined with Transcranial Magnetic Stimulation in individuals with Parkinson's disease (PD) improves phonation to a greater…
