Estimates of cost and saving effects of increasing rechargeable devices on the sustainability of a deep brain stimulation program
Objective: 1) To estimate deep brain stimulation (DBS) material costs for a 6-year-period at our institution considering two scenarios: a conservative one focused on gradual…Malignant neuroleptic syndrome following a sudden deep brain stimulation battery drain: Report of two cases
Objective: In this case report we present two cases of NMS associated with sudden drain of DBS batteries (37 years old Caucasian woman and 42…Mild Cognitive Impairment in Parkinson’s Disease Before and After Deep Brain Stimulation
Objective: To determine rates of mild cognitive impairment in Parkinson’s disease (PD-MCI) before and after deep brain stimulation (DBS) and to identify the specific cognitive…Transplantation therapy of human iPS cell-derived dopamine neural progenitor cells for Parkinson’s disease
Objective: To examine the efficacy of midbrain dopaminergic progenitors derived from human iPS cells, as the cell source for Parkinson's disease model mouse, by analyzing…An investigation of the potential neuroprotective role of curcumin in Parkinson’s disease patient-derived fibroblasts
Objective: To investigate if the protective effects of curcumin previously observed in SH-SY5Y cells are also found in patient-derived fibroblasts from Parkinson’s disease patients. Background:…Modified Frameless Stereotaxy for Gene Therapy in Pediatric Movement Disorder Patients
Objective: We have developed a modified frameless stereotaxic system for viral vector delivery of gene therapy in pediatric movement disorder patients with congenital enzyme deficiency.…Preclinical evaluation of a novel autologous substrate for cell-based therapy
Objective: Evaluate the survival and potential of brain-derived progenitor cells as a cell-based therapy(CBT) for Parkinson’s disease in a mouse xenograft and syngeneic rat model.…Vitamin B3 and Neurodevelopment in Parkinson’s Disease
Objective: This study aimed to investigate the potential of vitamin B3 to promote the conversion of stem cells to mature central nervous system (CNS) neurons.…Biofabricated tissue constructs to recapitulate the anatomy and functionality of the nigrostriatal pathway in Parkinson’s disease
Objective: 1) Biofabricate constructs that mimic the cytoarchitecture and function of the nigrostriatal pathway, and 2) Microinject constructs to assess restoration of dopaminergic input to…Bilateral stereotypy after unilateral cerebellar infarction
Objective: To report a case with bilateral hand stereotypy after left cerebellar infarction Background: Stereotypy is defined as repetitive and continuous non-goal-directed movement. It was…
