Eight contact LFP recordings in the Subthalamic region localize beta source to the dorsal STN
Objective: The aim of this study was to investigate the electrophysiological characteristics of intra and extra STN LFPs in PD to better locate the source…Phosphodiesterases and striatal pathways in Parkinson’s disease
Objective: To use phosphodiesterase (PDE)10A ([11C]IMA107) and PDE4 ([11C]Rolipram) positron emission tomography (PET) molecular imaging combined with diffusion tensor imaging (DTI) based probabilistic tractography to explore the expression…Objective gait parameters as a noninvasive biomarker for freezing of gait in Parkinson’s disease patients
Objective: To determine if steady-state gait parameters in Parkinson disease (PD) patients could serve as a predictive biomarker for freezing of gait (FOG). Background: FOG…Increased appendicular lean body mass is associated with increased cerebral cholinergic innervation in Parkinson disease
Objective: The main aim of this study was to examine the effect of cholinergic nerve terminal integrity in the brain on measures of sarcopenia. Background:…Optimization of Synucleinopathy and Nigrostriatal Degeneration Induced by Injection of Alpha-Synuclein Preformed Fibrils into Rat Striatum
Objective: Optimization of the surgical parameters (intrastriatal placement and concentration of alpha-synuclein preformed fibrils; α-syn PFFs) to increase the magnitude of nigrostriatal α-syn pathology and…Genetic knock-down of HDAC4 attenuates rotenone-induced abnormal expression of α-synuclein by affecting autophagic flux in SH-SY5Y Cells
Objective: To assess whether histone deacetylase 4 (HDAC4) is related to the abnormal expression of α-synuclein (α-syn) via the autophagy pathway. Background: The overexpression and…Vitamin D in the Parkinson’s Associated Risk (PARS) Study
Objective: The purpose of this study was to evaluate vitamin D levels in a population at risk for developing Parkinson’s disease (PD). Background: Vitamin D…Evaluation of CSF cytokine profiles in people with Parkinson disease and age-matched controls.
Objective: To investigate the levels of cytokines in the cerebrospinal fluid of subjects with Parkinson disease (PD) and matched healthy controls. Background: Neuroinflammation is thought…Deep Brain Stimulation (DBS) battery longevity of Medtronic Activa SC is briefer than preceding Soletra models, a within subject analysis
Objective: To contrast the durations of Activa SCs with the durations of preceding Soletra neurostimulator models within the same individuals programmed at near constant parameters.…The comparison of urine microvesicle reflecting gut microbiome between Parkinson’s disease and healthy control
Objective: The objective of this study to compare urine microvesicle between Parkinson’s disease(PD) and healthy controls Background: Recent researches showed that gut microbiome interact with central…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.