Inhibition of mitochondrial complexes induces unique transcriptomic and epigenetic profiles: implications to neurodegeneration induced movement disorders
Objective: To compare the neurotoxicological hallmarks induced by inhibitors of mitochondrial complex I (CI- 1- methyl-4- phenylpyridinium; MPP+), complex II (CII- 3- nitropropionic acid; 3-…Utility of a smartphone app in discretely assessing and monitoring symptoms of Parkinson’s disease
Objective: To assess the utility of a cognitive and motor battery on a smartphone/smart watch combination in an at-home setting for remote assessment of PD…Language characteristics of picture description task by Hebrew speaking patients with Parkinson’s disease
Objective: To characterize picture description by patients with PD Hebrew speakers. Background: Non-motor symptoms in Parkinson’s disease (PD) such as cognitive decline, depression and language…Clinical Correlates of Genetic and Biomarker Profiles in Patients with Progressive Supranuclear Palsy: Data from the ARISE Study
Objective: To characterize the genetic and biomarker profile of patients with Progressive Supranuclear Palsy (PSP) and the relationship of potential biomarkers with baseline disease severity.…Mechanisms underlying therapeutic group singing in persons with Parkinson’s disease
Objective: The objective of this study was to examine the potential mechanisms associated with improvement in clinical motor symptoms in persons with Parkinson’s disease (PD).…Effect of Medication Review on Reported Symptoms in Parkinson’s disease Patients
Objective: The objective was to analyse the effect of structured medication reviews (MR) in ambulatory PD patients on patient reported outcome measures (PROMS). Background: Patients…Does information from the Personal KinetiGraph™ (PKG) influence neurologists´ treatment decisions?
Objective: To evaluate if PKG data influences neurologists´ treatment decisions in routine clinical care of patients with Parkinson´s disease. Background: The PKG movement recording system is…Modeling of Parkinson’s disease by damaging dopaminergic neurons
Objective: Analysis of the simulation of Parkinson's disease in rats using 6-OHDA.Analysis of the simulation of Parkinson's disease in rats using 6-OHDA. Background: The mechanism…Wide distribution of alpha-synuclein oligomers in Creutzfeldt-Jakob disease detected by a novel proximity ligation assay
Objective: The objective of this work is to assess if oligomeric forms of alpha-synuclein exist in patients with Creutzfeldt-Jakob disease. Background: Prion diseases, the most…Metabolomic Analysis of Fecal Matter from Parkinsonian Mice
Objective: Assess the metabolic changes in fecal matter in mice treated with an immunomodulatory therapy. Background: The cause of neuronal death in Parkinson’s disease (PD)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.