Dopaminergic Neuroregeneration in the Diencephalon of 6-OHDA-Lesioned Adult Zebrafish-Based Parkinson’s Disease Model
Objective: This study established a 6-OHDA-lesioned adult zebrafish-based PD model and investigated the neuroregenerative processes of diencephalic dopaminergic neurons (DpN). Background: Studies on endogenous neuroregeneration…Healthcare Resource Utilization and Costs of Parkinson’s Disease Dementia With Psychosis in the US Medicare Population
Objective: To describe healthcare resource use (HCRU) and related costs among Parkinson’s patients with dementia (PDD) and psychosis compared with other dementia types in a…A case of hemimasticatory spasm with well therapeutic response to serial injections of botulinum toxin
Objective: To report a case with hemimasticatory spasm responsive to serial botulinum toxin injections. Background: Hemimasticatory spasm is a rare neurologic disorder characterized by involuntary…The carotid ultrasonography revealed vagus nerve atrophy of the patients with parkinsonism
Objective: This study aims to clarify the compare vagus nerve atrophy with Parkinson’s disease (PD) and other atypical parkinsonism. Background: Although the pathogenesis of the…Enhancing the Proteasomal Degradation of Alpha Synuclein: “The Hallmark” to attenuating the Progression of Parkinson’s Disease
Objective: The research aimed at preventing the accumulation of Alpha Synuclein in order to prevent it's accumulation. It is imperative that we also establish that…Communication Calendar for Interdisciplinary Therapy of Parkinson’s Disease
Objective: To develop a communication calendar (CC) to facilitate information exchange amongst therapists involved in interdisciplinary therapy of Parkinson's Disease (PD). Background: Increasing complexity of…Population Exposure-Response Models of Apomorphine Sublingual Film in Healthy Subjects and Patients With Parkinson’s Disease and “OFF” Episodes
Objective: Exposure-response models were developed to characterize the relationship between apomorphine exposure and (1) efficacy using Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease…Population Exposure-Response Modeling of the Effects of Apomorphine Sublingual Film on QTc in Patients With Parkinson’s Disease and “OFF” Episodes
Objective: To characterize the relationship between plasma apomorphine concentrations and QTc (QT interval corrected for heart rate) in patients with Parkinson’s disease (PD) and “OFF”…Gender differences in Motor symptoms, Non-Motor symptoms and Quality of Life in Parkinson’s disease: COPPADIS-2015 study cohort
Objective: To assess gender differences among PD patients and health controls (HC) of the COPPADIS-2015 study cohort. Background: Men and women are different in genetic,…Validation of the diagnostic criteria for progressive supranuclear palsy in pathologically confirmed patients
Objective: To assess the sensitivity and specificity of the diagnostic criteria for progressive supranuclear palsy (PSP). Background: The International Parkinson and Movement Disorder Society criteria…
