Long-Term Effects of LPS and Alcohol in Rats: A Model of Neuro-Degenerative Disease
Objective: We postulate alterations of the intestinal barrier (or leaky guts) enhances inflammation, as well as the production of alpga (α)-synuclein which has characteristic pathological…Abnormal respiratory rate and patterns in MSA
Objective: To evaluate respiratory rate and patterns in patients with Multiple Systems Atrophy (MSA). Background: One of the primary clinical features of multiple system atrophy…Synaptic function in Parkinson’s disease associated with GBA mutations
Objective: To investigate the pathological substrate of impaired cognition in Parkinson’s disease (PD) associated with glucocerebrosidase (GBA) mutation. Background: Mutations in glucocerebrosidase gene (GBA), originally…Striatal dopaminergic regulation of micrographia in parkinsonism
Objective: To investigate the role of brain dopamine function in writing and drawing micrographia of patients with parkinsonism. Background: Micrographia, an abnormally small or progressively…Long-term adherence with wearing a multi-sensor watch in the Personalized Parkinson Project
Objective: We assessed long-term participant engagement with a multi-sensor watch for continuous daily life monitoring among people with Parkinson’s disease. Background: Wearable sensors can potentially…Real-life gait performance as a marker for motor fluctuations: the Parkinson@home Validation study
Objective: To assess the feasibility of using real-life gait performance derived from a single wearable as a marker for motor fluctuations in Parkinson’s disease (PD).…Hip fracture in patients with a new diagnosis of Parkinson’s Disease – estimating the 5-year risk
Objective: We set out to quantify the five-year risk of hip fracture for a cohort of 780 patients for whom a new diagnosis of Parkinson’s…Pattern and Presentation of Parkinson Disease in two Teaching Hospitals in Enugu, South East Nigeria
Objective: To describe the pattern of presentation of Parkinson disease in patients attending medical out-patient clinic in Enugu South East Nigeria. Background: Parkinson Disease is…Levodopa response in later stages of Parkinson’s disease: a case-control study
Objective: To compare the response of motor and non-motor symptoms (NMS) to a L-dopa challenge test between late stage (LS) PD patients and advanced stage…Long-term effect of levodopa-carbidopa intestinal gel on axial signs in Parkinson’s disease
Objective: To investigate the long-term effect of levodopa-carbidopa intestinal gel (LCIG) on axial signs in Parkinson's disease (PD) patients and the related prognostic factors. Background:…
