MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Composite UHDRS shows extensive spatial correlation with grey matter and white matter volume in Huntington’s disease gene carriers

    C. Estevez-Fraga, E. Johnson, F. Rodrigues, P. Zeun, A. Durr, D. Langbehn, B. Leavitt, R. Roos, S. Gregory, R. Scahill, G. Rees, S. Tabrizi (London, United Kingdom)

    Objective: This work sought to determine the structural correlates of variability in cUHDRS in HD gene expansion carriers (HDGC). Background: Symbol digit modalities test (SDMT),…
  • 2019 International Congress

    Impaired cerebral vasoreactivity in patients with Parkinson’s disease: clinical and imaging correlates

    I. Estrada-Bellmann, D. Cantú-García, S. Castillo-Torres, A. Mendoza-García, H. Sánchez-Terán, D. Díaz-Pérez, D. Roque-Martínez, S. Saldívar-Dávila, H. Martínez, T. Moreno-Andrade, B. Chávez-Luévanos, F. Góngora-Rivera (Monterrey, NL, Mexico)

    Objective: To determine the clinical and imaging correlates of impaired cerebral autoregulation as measured with cerebral vasoreactivity (CVR) in patients with idiopathic Parkinson’s disease (PD).…
  • 2019 International Congress

    Depressive Symptoms are Associated with Lower Locus Coeruleus Volumes in Parkinson’s disease

    C. Farrell, G. Pagano, E. de Natale, M. Politis (London, United Kingdom)

    Objective: To assess locus coeruleus volumes in Parkinson's disease patients with depressive symptoms. Background: Depression associated with Parkinson disease (PD) has a different symptom profile…
  • 2019 International Congress

    Dynamic functional connectivity signature of cognitive decline in Parkinson’s disease

    E. Fiorenzato, A. Strafella, J. Kim, R. Schifano, L. Weis, A. Antonini, R. Biundo (Venice, Italy)

    Objective: Aim of the present study was to characterize the dynamic changes of functional connectivity associated with Parkinson’s disease (PD) cognitive decline using dynamic functional…
  • 2019 International Congress

    Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD

    J. Fu, M. Matarazzo, I. Klyuzhin, K. Cheng, C. Bevington, J. Mckenzie, N. Heffernan, E. Shahinfard, M. Mckeown, AJ. Stoessl, V. Sossi (Vancouver, BC, Canada)

    Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…
  • 2019 International Congress

    Usefulness of Cardiac MIBG Scintigraphy, DAT scan and midbrain/pontine ratio to differentiate Parkinson disease from atypical parkinsonian syndrome

    H. Fujita, K. Suzuki, Y. Watanabe, M. Hamaguchi, K. Hirata (Mibu, Japan)

    Objective: The purpose of this study was to evaluate the usefulness of cardiac 123I-metaiodobenzylguanidine (MIBG) uptake, Dopamine transporter (DAT) scan and midbrain/pontine ratio (M/P ratio)…
  • 2019 International Congress

    Imaging biomarker for progression of motor symptoms in advanced Parkinson’s disease

    K. Furukawa, N. Sawamoto, A. Shima, D. Kambe, A. Nishida, I. Wada, H. Sakamaki, K. Yoshimura, Y. Fushimi, T. Okada, K. Togashi, R. Takahashi (Kyoto, Japan)

    Objective: The aim of the present study is to clarify correlation between motor deficits and dopaminergic neuronal loss in advanced Parkinson’s disease (PD). Background: Series…
  • 2019 International Congress

    Changes in Neuromelanin MRI Signal in Parkinson’s Disease: A Longitudinal Study

    R. Gaurav, L. Yahia-Cherif, G. Mangone, N. Pyatigorskaya, R. Valabregue, C. Ewenczyk, M. Hutchison, J. Corvol, M. Vidailhet, S. Lehéricy (Paris, France)

    Objective: To investigate the neuromelanin (NM) signal changes in Parkinson’s disease (PD) patients associated with disease progression. Background: PD is characterized by the progressive loss…
  • 2019 International Congress

    Functional MRI activation during the Symbol Digit Modalities Test in Parkinson’s disease

    G. Grolez, R. Viard, R. Lopes, JP. Pruvo, K. Dujardin, L. Defebvre, C. Moreau (Lille, France)

    Objective: To assess alterations in functional brain activation patterns related to mental slowing in patients with Parkinson’s disease (PD). Background: Attentional deficits, namely mental slowing,…
  • 2019 International Congress

    Longitudinal Analysis of the Corticospinal tract microstructure in Parkinson’s Disease Patients

    R. Guimarães, L. Piovesana, P. Azevedo, B. Campos, F. Cendes (Campinas, Brazil)

    Objective: To assess longitudinal abnormlities throughout  the corticospinal tract in Parkinson’s Disease patients. Background: Parkinson’s Disease (PD) is a neurodegenerative progressive disease might become a pandemic…
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