Urate Levels and Risk of Parkinson’s Disease：A Two-Sample Mendelian Randomization Study
Objective: To investigate the causal relationship between circulating serum urate levels and the risk of Parkinson's disease (PD) using a two-sample Mendelian randomization (MR) approach.…Incidence and movement disorders associated with Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in the Princess Maha Chakri Sirindhorn Medical Center (MSMC)
Objective: To identify incidence and clinical features of SREAT patients in MSMC. Background: SREAT patients could present with encephalopathy with various neurological abnormalities, including behavioral…Does Fgatir Hypointensity Predict Outcomes After Deep Brain Stimulation For Action Tremors
Objective: To test whether efficacy of Deep Brain Stimulation (DBS) in different action tremor syndromes (Essential tremor, ET, ET-plus, or dystonic tremor as per IPMDS…Comprehensive Diagnostic Accuracy of α-Synuclein Seed Amplification Assays Across Non-Parkinsonian Synucleinopathies: A Systematic Review and Diagnostic Meta-analysis
Objective: To evaluate the diagnostic accuracy of αSyn-SAAs across established and prodromal non-Parkinsonian synucleinopathies, including Lewy body disorders (DLB), multiple system atrophy (MSA), isolated REM…Homozygous PRRT2 Frameshift Mutation Presenting with Infantile Onset Seizures and Childhood Episodic Ataxia
Objective: To report a rare presentation of a homozygous PRRT2 frameshift mutation manifesting as infantile-onset seizures followed by childhood episodic gait imbalance. Background: PRRT2 mutations…Multimodal Elastography-Assisted Quantitative Evaluation Tool for Diagnosing Rigidity in Parkinson’s Disease
Objective: To investigate the feasibility of multimodal elastography for quantifying rigidity in PD and to screen for diagnostically valuable muscle indicators to construct a non-invasive…Perception of Early-Intervention Therapies and Clinically Meaningful Delays in Huntington’s Disease Onset and Progression: The Pre-HDBOI Study
Objective: To characterize willingness among people with premanifest Huntington’s disease (PwPHD) to consider early-intervention therapies if available, the minimally acceptable delay in HD onset/progression, and…Real-world database analysis of new-onset hypotension and medications for orthostatic hypotension prescribing patterns in patients with Parkinson’s Disease receiving MAO-B Inhibitors and levodopa in Japan
Objective: To evaluate the incidence of claims-defined new-onset hypotension and the prescribing patterns of medications for orthostatic hypotension in patients with Parkinson’s disease (PD) treated…A 6-month Pilot Study of Disease-Modifying Potential of Long-term Transcutaneous Auricular Vagus Nerve Stimulation in Parkinson’s Disease
Objective: To investigate the efficacy and potential disease-modifying effects of of long-term transcutaneous auricular vagus nerve stimulation(taVNS) in patients with early-stage Parkinson's Disease(PD). Background: PD currently lacks established disease-modifying…Diagnostic Accuracy of NPH by Radiographic Suspicion and Effect on Patient Outcomes
Objective: Our study examines the radiographic accuracy when suggesting normal pressure hydrocephalus (NPH), correlation with imaging study indication, and frequency of lumbar puncture (LP) for…
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