Characterization of color vision impairment in Lewy Body Diseases
Objective: We sought to characterize the prevalence of color vision impairment in DLB patients and investigate how color vision impairment in DLB patients was associated…Dielectric Properties of Blood Plasma Predict Cognitive Impairment in an Amyloid-Beta-Induced Rat Model of Alzheimer’s Dementia
Objective: This study presents a novel method of predicting the behavioral pattern in male Sprague-Dawley rats with impaired learning and memory, based on the measurement…Quantitative EEG and medial temporal lobe atrophy in early Parkinson’s disease with behavioral and psychological symptoms
Objective: We aimed to assess the relationship between EEG abnormalities and MTLA, and its clinical validity in Parkinson’s disease with behavioral and psychological symptoms. Background:…Assessing the Effectiveness of Valbenazine in the Treatment of Tardive Dyskinesia as Determined by the AIMS and PGIC: Results from the KINECT 4 Trial
Objective: To assess the long-term effects of once-daily valbenazine on tardive dyskinesia (TD). Background: Valbenazine has been evaluated in several long-term TD studies, including the…Abnormal signaling along the non-canonical molecular cascade GRK6/β-arrestin2/Akt/GSK-3β in the putamen is associated with tardive dyskinesia following chronic haloperidol exposure in a primate model
Objective: To investigate the neurochemical basis of tardive dyskinesia (TD) in an experimental primate model. Background: TD is a potentially irreversible motor complication occurring in…Fasciculations from a cholinesterase inhibitor
Objective: Present and discuss fasciculations in the setting of acetylcholinesterase inhibitors. Background: Specific acetylcholinesterase (AChE) inhibitors (e.g., donepezil, rivastigmine, galantamine) are the current first-line treatment…Ballism as major manifestation in Neuroleptic Malignant Syndrome in a patient toxoplasmosis cerebri
Objective: To present clinical feature Neuroleptic Malignant Syndrome (NMS) in Toxoplasma cerebri, a rare case. Background: Neuroleptic malignant syndrome (NMS) is a rare case, life-threatening…Patients experiencing peak-dose dyskinesia use re-distribution of involuntary movement amplitude throughout their body to minimize the functional impact of dyskinesia
Objective: To investigate the presence of a strategy in dyskinesia amplitude re-distribution enabling patients to perform motor tasks. Background: In Parkinson’s disease (PD), occurrence of…Intrastriatal Fyn silencing as a gene therapy strategy to manage levodopa induced dyskinesia in a mice model of Parkinson’s disease
Objective: To genetically abrogate Fyn expression to reduce levodopa induced dyskinesia (LID) in the 6-OHDA mice model of Parkinson’s disease (PD), using intrastriatal-injected lentiviral (LV)…An oculogyric crisis after administation of alizapride: A tardive phenomenon?
Objective: We present a case of an oculogyric crisis (OGC) after administration of alizapride. Curious about this case is that the OGC only happened after…
