MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Classifying Parkinsonian Gait and Turning in Daily Life with Wearable Technology

    F. Horak, J. McNames, M. El Gohary, J. Nutt, C. Curtze (Portland, OR, USA)

    Objective: We aim to determine the set of gait and turning measures from wearable technology that best separate mobility during daily life in people with…
  • 2018 International Congress

    Development of anti-amyloid drugs for Parkinson’s disease by combination screening of high-throughput in vitro assay and phenotype-based C. elegans system

    K. Ikenaka, K. Araki, S. Sonoda, T. Takeuchi, Y. Nagai, Y. Goto, H. Mochizuki (Suita, Japan)

    Objective: To establish a new combination screening system consisted of high-throughput in vitro assay with phenotype-based in vivo assay and to develop anti-amyloid drugs truly…
  • 2018 International Congress

    Level of serum Mortalin in Parkinson’s disease correlating with -Synuclein: Assessment of protein marker for early detection

    S. Dey, A. Singh, T. Bajaj, A.B. Dey (New Delhi, India)

    Objective: This study aims to quantify and correlate Mortalin and α-Syn protein in serum of Parkinson's disease patients and develop it as protein marker for…
  • 2018 International Congress

    Effects of non-invasive brain stimulation on motor-speech disorders in Parkinson’s disease

    I. Rektorova, P. Klobusiakova, L. Brabenec, J. Mekyska, Z. Galaz, M. Kostalova (Brno, Czech Republic)

    Objective: To investigate acute effects of repetitive transcranial magnetic stimulation (rTMS) of the motor and auditory feedback area on hypokinetic dysarthria in Parkinson’s disease (PD)…
  • 2018 International Congress

    Combined catechol-O-methyl-transferase inhibition and intrajejunal Levodopa infusion: A real-life single-centre experience

    R.N. Taddei, V. Leta, A. Sauerbier, M. Parry, A. Podlewska, L. Hall, S. Tentis, P. Odin, W. Poewe, P. Dubois, D. van Warmelen, E.W. Lim, K.R. Chaudhuri (London, United Kingdom)

    Objective: To explore if catechol-O-methyl-transferase inhibition (COMT-I) can prolong the efficacy of daytime intrajejunal Levodopa infusion (IJLI) in Parkinson’s disease (PD) along with a reduction…
  • 2018 International Congress

    Effectiveness of Rotigotine plus Intensive and Goal-based Rehabilitation versus Rotigotine alone in “de-novo” Parkinsonian subjects: A Randomized Controlled Trial with 18-month Follow-up

    D. Ferrazzoli, P. Ortelli, G. Riboldazzi, R. Maestri, G. Frazzitta (Gravedona ed Uniti, Italy)

    Objective: To evaluate the synergism between Dopamine Replacement Therapy (DRT) and rehabilitation in treating Parkinson's disease (PD), by investigating the short and the long-term effectiveness…
  • 2018 International Congress

    Multi-modal retention in a phase III clinical trial in early Parkinson disease (STEADY-PD III)

    B. Greco, R. Holloway, K. Hodgeman, S. Henderson, C. Tarolli, K. Biglan, T. Simuni (Rochester, NY, USA)

    Objective: To evaluate novel retention strategies in an ongoing phase 3 clinical trial in individuals with Parkinson disease (PD). Adequate participant retention is a significant…
  • 2018 International Congress

    Challenging mitochondria in idiopathic Parkinson‘s disease fibroblasts

    P. Antony, O. Boyd, K. Mommaerts, K. Sokolowska, M. Ostaszewski, A. Baumuratov, L. Longhino, F. Poulain, R. Krueger, R. Balling, N. Diederich (Belvaux, Luxembourg)

    Objective: Evaluate mitochondrial integrity in cultivated fibroblasts of patients with idiopathic Parkinson’s disease (IPD) and healthy controls (HC). Background: Mitochondrial dysfunction (MD) is considered an…
  • 2018 International Congress

    Comparison of low versus high frequency stimulation on stuttering in Parkinson’s disease patients with bilateral subthalamic nucleus deep brain stimulation

    O. Jitkritsadakul, K. Boonpang, R. Bhidayasiri (Bangkok, Thailand)

    Objective: The objective of this study was to identify the prevalence of stuttering in PD patients with bilateral STN DBS compared to medically-treated PD (PD-MED)…
  • 2018 International Congress

    Effect of exercise on neurodegenerative parkinsonism unmasked by dopamine blocking drugs (DRBD)

    J. Morley, S. Wood, G. Cheng, K. Browne, K. Robinson, D. Weintraub, J. Duda (Philadelphia, PA, USA)

    Objective: To test whether aerobic walking influences clinical status, biochemical and radiologic markers associated with degenerative parkinsonism unmasked by DRBD. Background: Failed trials of putative…
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