A novel mGlu4 PAM alleviates motor symptoms in primate models of PD and of LID
Objective: Objective was to assess the therapeutic potential of our novel mGlu4 positive allosteric modulator (PAM), foliglurax, as an anti-parkinsonian treatment in gold-standard primate models.…Clinical characteristics of turkish patients with Parkinson’s disease: A retrospective analysis of 428 patients
Objective: To evaluate the demographic, motor and non-motor clinical characteristics of Turkish Parkinson’s disease (PD) patients in our Movement Disorders Outpatient Clinic. Background: Although PD…Longitudinal observational study on late onset Parkinson’s disease over a decade
Objective: 1. To analyse the outcome of Late onset Parkinson’s disease over ten year period. 2. To look for any relationship between Initial cognition to…The effectiveness of boxing exercise in elderly patients including Parkinson’s disease patients
Objective: To clarify the effect of boxing exercise on balance, muscle strength and mobility in elderly patients with chronic disease including Parkinson’s disease (PD). Background:…Evaluation of the interaction between safinamide and opicapone in Parkinson’s disease patients with fluctuations
Objective: To describe and to evaluate a Balearic ongoing Parkinson's disease (PD) Project to evaluate the efficacy and tolerance of the interaction between safinamide and…Home based exercises to reduce falls in people with Parkinson’s disease: A randomized trial
Objective: To measure the outcomes of a six week, twice weekly, home physiotherapy exercise and falls education program on falls, mobility and quality of life…DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Visualization of Optimal Directionally Stimulated Anatomy
Objective: To visualize the volumes of activated tissue in relation to the neuroanatomy for the optimal stimulation parameters in Ring Mode (omnidirectional) stimulation in comparison…Directional Lead Impedances and Their Possible Effects on Deep Brain Stimulation
Objective: The objective was to characterize the possible effects that directional leads impedances have on Deep Brain Stimulation (DBS) therapy. Background: DBS of the subthalamic…Occurrence of dopaminergic adverse-events in patients that switched from entacapone to opicapone: The BIPARK-I open-label experience
Objective: To assess the occurrence of dopaminergic adverse-events (AEs) in levodopa-treated Parkinson’s Disease (PD) patients that switched from entacapone (ENT) to opicapone (OPC) in the…The BeyoND study: Design and baseline characteristics of a study evaluating the long-term safety of ND0612 for motor fluctuations in Parkinson’s disease
Objective: Describe the design and baseline characteristics of a long-term (1 year) study of 2 ND0612 dose regimens, with emphasis on systemic and local safety…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.