Treating Huntington’s Disease using a holistic approach
Objective: Huntington’s disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. It deteriorates a person’s physical…Cognitive Reserve and Physical Activity Modulate Functional Brain Re-organisation in Premanifest Huntington’s Disease: Preliminary Evidence
Objective: In this study, for the first time we examined the relationship between cognitive reserve, sleep quality and current level of physical exercise and functional…Investigating the clinical predictors of depression in Huntington’s disease: An Enroll-HD Database Study
Objective: This study was designed to investigate clinical predictors of depression in subjects with HD. Background: Huntington’s disease (HD) is characterized by motor, cognitive and…Comparing risperidone and olanzapine to tetrabenazine for the management of Huntington’s chorea
Objective: To compare the efficacy of risperidone and olanzapine to tetrabenazine (TBZ) for the management of Huntington’s chorea in Enroll-HD participants. Background: TBZ is provenly-effective…The impact of bilingualism in brain structure and function in early and mild Huntington’s disease
Objective: To explore the impact of different levels of lifelong use of bilingualism on brain structure and metabolism in early and mid-stage Huntington’s disease (HD);…Prevalence of Single Nucleotide Polymorphisms (SNPs) rs362307 or rs362331 in Patients with Huntington’s Disease
Objective: An observational research study is being conducted in patients with Huntington’s disease (HD) to determine the frequency with which the thymine (T) variant of…Neurofilament light protein: An emerging clinical and translational biofluid biomarker for Huntington’s disease
Objective: To investigate whether neurofilament light protein (NfL) a potential prognostic marker of neurodegeneration with Huntington’s disease. Background: NfL, a component of the axonal cytoskeleton,…Huntington disease like 2 in South Africa
Objective: Background: Since the Huntingtin gene was identified in 1993, it has been recognized that a small proportion of patients with a clinical syndrome resembling…Neuroprotective role of cinnamaldehyde against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease
Objective: The present study examined the potential therapeutic effects of CA against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD and explored…A Study on Combined Brain Positron Emission Tomography (PET) – Magnetic Resonance Imaging (MRI) Using Fluorodeoxyglucose (18FDG) (FDG-PET/MRI) in Premanifest Huntington’s Disease Gene-expansion Carriers
Objective: By a combined brain PET–MRI using FDG, we wished to simultaneously characterize the structural and metabolic brain changes in premanifest HD gene-expansion carriers. Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.