Association of Olfaction dysfunction with Brain Microstructure in Prodromal Parkinson disease
Objective: Investigating the association between olfactory dysfunction and connectometry patterns in UPSIT-matched prodromal and PD patients. Background: Parkinson’s disease (PD) is a heterogeneous neurodegenerative disease…Long-term and dopamine dependent dynamics of subthalamic nucleus local field potentials in Parkinson’s disease
Objective: Using a new deep brain stimulation (DBS) pulse generator device that can record local field potentials (Activa PC+S, Medtronic Inc.), the current experiment investigated…A comprehensive digital biomarker active testing and passive monitoring suite for the remote and frequent assessment of motor symptom progression in Parkinson’s disease
Objective: We present the development and design of a comprehensive digital biomarker smartphone application (app) for remote and frequent assessments of motor symptom severity and…Neuroinflammation Predicts Dompaminergic Deficit in Early Parkinson Disease: DAT SPECT Imaging Study
Objective: We aimed to investigate whether striatal Dopamine transporter (DaT) uptake could be predicted by Neutrophil to lymphocyte ratio (NLR) or measures of disease severity…The usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at a movement disorder clinic
Objective: The aim of this study was to determine the usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at our movement disorder clinic…Identifying the neural correlates of doorway freezing in Parkinson’s disease
Objective: We aimed to combine a previously validated virtual reality gait paradigm with functional Magnetic Resonance Imaging (fMRI) to investigate the neural correlates underlying doorway-provoked…The neural effects of a randomized controlled cognitive training program for treating freezing of gait in Parkinson’s disease
Objective: This study set out to investigate whether a targeted cognitive training program (CT) induced neural plasticity processes associated with reduced propensity for freezing of…Abnormal Functional Connectivity in Cerebellar Locomotor Region is associated with the severity of freezing of gait in patients with Parkinson’s disease
Objective: We aim to analyze cerebellar functional connectivity (FC) in PD patients with FOG (PD-FOG). Background: Freezing of gait (FOG) is a disabling disorder frequently…Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson’s disease patients
Objective: To study microstructural changes in grey and white matter in early drug-naïve Parkinson's disease (PD) patients and correlate these changes with neuropsychological manifestations. Background:…Optimization of deep brain stimulation in STN among patients with Parkinson’s disease using a novel EEG-based tool
Objective: The current study aims to develop an innovative method for objective differentiation between the locations of the four DBS contacts in the various parts…
