Rehabilitation Following Initiation of Device Assisted Treatment in Parkinson’s Disease – a Randomized Controlled Trial
Objective: To investigate if coordinated rehabilitation after starting Device Assisted Treatment (DAT) improves daily activity performance/skills, participation, and disease specific quality of life. Background: DATs…Translational evaluation of CSF as a relevant compartment for assessing target engagement of therapeutic anti–α-syn antibodies.
Objective: To evaluate a translational free/total α-synuclein (α-syn) assay framework to quantify in vivo target engagement (TE) of anti–α-syn antibodies in preclinical models and to…Extracellular vesicle–based characterization of synaptic dysfunction in early Parkinson’s disease
Objective: To establish a method that allows for investigating early synaptic dysfunction in Parkinson’s disease (PD) by analyzing CNS-derived extracellular vesicles and assessing their effects…Microstructure predicts cognition after Neurostimulation in Parkinson’s disease
Objective: To identify preoperative microstructural markers that are associated with postoperative changes in cognition. Background: Subthalamic deep brain stimulation (STN-DBS) represents an established therapeutic intervention…“Most of us are improvising with the work we are doing”: Perspectives of health and social care professionals in Ghana and Kenya on mobility management for Parkinson’s disease
Objective: To explore perspectives of health and social care professionals (HSCPs) in Ghana and Kenya on clinical mobility management for Parkinson’s disease (PD). Background: Mobility…Sensor-based assessment of axial symptoms in Parkinson’s disease
Objective: To investigate whether inertial sensor–derived metrics can objectively quantify axial symptoms in Parkinson’s disease (PD), focusing on posture and postural instability. Background: Axial symptoms…Tremor in Oromandibular Dystonia
Objective: To determine the prevalence of tremor in patients with oromandibular dystonia, characterise its anatomical distribution relative to dystonic regions, and assess the relationship between…Risk Factors and Etiologies for Emergency Visit among Parkinson´s Disease Patients: a Narrative Review
Objective: The objective of this study is to understand various risk factors and etiologies of PD patients for admission at emergency department. Background: Parkinson´s Disease…Investigating the Causal Relationship Between Tofu Intake and Parkinson’s Disease in the Asian Population Using Mendelian Randomization
Objective: This study aims to evaluate the causal effect of tofu consumption on the risk of Parkinson’s disease (PD). Background: Tofu is a soy-derived food…Higher Dopaminergic Sensitivity Underlies Dyskinesia Occurrence in Indigenous Sabahan PRKN Parkinson’s Disease
Objective: To compare dyskinesia occurrence and associated factors in PRKN versus non-PRKN early-onset Parkinson's Disease (EOPD). Background: Biallelic pathogenic PRKN variants represent the commonest recessive…
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