A Case of Anti-NMDA Receptor Encephalitis Presenting with Refractory Myoclonus and Perioral Dyskinesia during the First Trimester of Pregnancy
Objective: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder often presenting with psychiatric symptoms, seizures, and characteristic movement disorders such as orofacial dyskinesia. Its occurrence…Mild Motor Impairments in Rapid Eye Movement Behavior Disorder: Tremor and Bradykinesia
Objective: We investigated patients with RBD to identify mild motor impairments through the objective quantification of sensitive motor control assays. Background: It is established that…The Diagnostic Value of Dopaminergic-Glucose United PET Imaging in Parkinson’s disease
Objective: This study aimed to evaluate the diagnostic efficacy of DAT-FDG united PET imaging in differentiating PD from other parkinsonian disorders in real-world clinical settings…Multimodal Quantitative MRI Improves Parkinson’s Disease Classification
Objective: To evaluate multimodal MRI discrimination of Parkinson’s disease using RPCA–kNN and associations with MDS-UPDRS. Background: Parkinson’s disease (PD) involves progressive neurodegeneration affecting basal ganglia…Synuclein and dopamine transporter biomarkers among phenoconverters to parkinsonian disorders
Objective: To describe and assess biological congruency, defined as expected biological profile based on abnormal CSF α-synuclein Seed Amplification Assays (CSFaSynSAA) and dopamine transporter SPECT…Prodromal Parkinson’s Disease in Singapore: Motor and Non-Motor Symptom Patterns
Objective: To determine the differences in motor and non-motor symptoms between subjects categorized as Low, Intermediate, or High Risk for future Parkinson’s Disease (PD). Background:…L-DOPA Metabolism as a Function Related to the Potency of iPSC-Derived Dopaminergic Progenitor cells
Objective: This study aimed to elucidate how iPSC-derived dopaminergic progenitor cells (iPSC-DAPs) acquire the ability to metabolize L‑DOPA in vitro and to evaluate whether the…Repurposing Rifabutin for Neuro-Metabolic Disorders: AMPK-PGC-1α-Driven Mitochondrial Protection in Diabetes Associated Parkinsonism
Objective: To assess the role of rifabutin in restoring mitochondrial function and energy balance through modulation of the AMPK–PGC-1α signaling pathway in diabetes-related Parkinsonism. Background:…A Machine Learning-Based Approach to Identify Responders to Electrosonic Brain Stimulation in Parkinson’s Disease
Objective: To determine whether baseline motor phenotyping with the Integrated Motion Analysis Suite (IMAS), a multimodal sensor-based assessment platform, can identify clinically meaningful Parkinson’s disease…Racial Disparities in End-of-Life Care among Patients with Advanced Movement Disorders in an Interdisciplinary Supportive Care Clinic
Objective: To examine whether an interdisciplinary supportive care clinic model mitigates racial disparities in advance care planning (ACP), hospice utilization, and place of death among…
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