Low body weight is associated with poor functional status in Parkinson’s disease (PD)
Objective: To assess if low body weight and malnutrition is associated with poor functional status in PD. Background: It has been observed that many advanced…Effects of neural stem cell transplantation on the differentiation of dopaminergic neurons in the substantia nigra and changes to rotational behavior of Parkinson’s disease rats
Objective: To explore the effects of neural stem cells transplantation on the differentiation of substantia nigra dopaminergic neurons and on the rotational behavior in a…Bidirectional gut-to-brain and brain-to-gut propagation of α-synuclein pathology in non-human primates
Objective: The prototypic synucleinopathy Parkinson's disease (PD) is hypothesized to spread out from the enteric nervous system (i.e. the gut) via the vagal nerve up…Relationship of Vitamin D deficiency with Parkinson’s disease risk
Objective: To study the level of vitamin D in the serum of Parkinson’s disease patients in the involvement of disease risk. Background: The Parkinson’s disease…Substantia nigra hyperechogenicity is similarly enlarged in Gaucher and in GBA mutation carriers
Objective: Testing the role of glycolipid accumulation in the risk for Parkinson's disease. Background: Increased risk for Parkinson's disease is well known among carriers of…Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort
Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…Motivational effects on action selection and memory
Objective: Eye movements provide important insights into the pathophysiology of neurological disorders. Here two paradigms were devised to quantify effects of motivation on motor control…Levodopa-induced dyskinesia in Parkinson’s disease: Sleep matters
Objective: To investigate the relationship between slow wave activity (SWA) of non-rapid eye movement (NREM) sleep, which underlies adjustment of cortical excitability, and levodopa-induced dyskinesias…Influence of dopamine deficiency on interhemispheric crosstalk in Parkinson’s disease
Objective: To identify the significance of dopaminergic depletion in Parkinson’s disease (PD) on interhemispheric crosstalk using a complex bimanual tapping task. Background: Dopamine deficiency in…Profiles of microRNA in cerebrospinal fluid could be potential biomarkers for identifying motor subtype of Parkinson’s disease
Objective: We investigated CSF miRNA expression in PD and control subjects. We also evaluated if specific miRNA were differently expressed according to motor subtype of…
