Serum Leptin levels in Iranian patients with Parkinson’s disease
Objective: Parkinson’s disease (PD) is the second most common neurodegenerative disorder that frequently affects elderly population worldwide. Initially, PD was known as a motor disorder…Microbiota DNA in the blood of patients with Parkinson’s disease
Objective: The aim of this study was to explore the blood microbiota compositions in Chinese patients with Parkinson’s disease (PD). Background: Emerging evidences suggest that…Catecholamines interrelation in plasma of early diagnosed treatment-naive patients with Parkinson disease
Objective: To investigate the interrelation of catecholamines in the blood plasma of healthy people and PD patients. Background: The study “START-1” was funded by Investment…Unraveling gut microbiota in Parkinson’s disease and atypical parkinsonism
Objective: (1) To evaluate the differences in gut microbiota among Parkinson’s disease (PD), atypical parkinsonism (i.e. multiple system atrophy [MSA] and progressive supranuclear palsy [PSP])…Spatiotemporal patterns of direct and indirect pathway striatal projection neurons in mouse model of Parkinson’s disease and dyskinesia
Objective: To identify patterns of striatal projection neurons (SPN) activities that code for akinetic and dyskinetic movement disorders in a mouse model of hemiparkinsonism and…Interaction of TDP-43 with IAPP in pancreatic beta cells of patients with sinucleinopathies
Objective: We have investigated whether deposits of phosphorylated TDP-43 might be present in pancreatic tissue of patients with synucleinopathies. Background: The TAR DNA binding protein…Bmal1 deficiency aggravates MPTP-induced dopaminergic cell death through promoting neuroinflammation
Objective: Bmal1 is one of the most important central clock genes of circadian rhythm. Circadian rhythm dysfunction is one of the non-motor symptoms in Parkinson’s…Characterization of the preclinical model parkinQ311X
Objective: To characterize the preclinical model parkinQ311X. Because the PARK2-associated disease in humans is characterized by juvenile onset and slow progression, in order to clarify…Neuroprotection effects of probiotics strains on a chronic MPTP-induced mouse model of Parkinson’s disease
Objective: To explore the effects of probiotics strains on the neuroinflammation and degeneration of dopaminergic neurons in chronic Parkinson’s disease (PD) mice model. Background: Microglia-mediated…Tau and α-synuclein autoantibodies as potential biomarkers for Parkinson’s and Alzheimer’s diseases
Objective: To investigate the value of the naturally occurring serum AIAs of α-synuclein (α-syn) and tau, proteins as potential biomarker for diagnosis of PD in…
