MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Identification of putative serum biomarkers for parkin-related Parkinson’s disease by metabolome analysis

    T. Ogawa, T. Hatano, A. Okuzumi, S. Ueno, A. Mori, Y. Oji, M. Fujimaki, T. Koinuma, S. Saiki, N. Hattori (Tokyo, Japan)

    Objective: Parkin is known as the causative gene of autosomal recessive familial Parkinson’s disease (parkin-PD). It remains unclear how parkin dysfunction associates with the dopaminergic…
  • 2018 International Congress

    Red cell distribution with levels in Parkinson’s disease patients

    G. Ozgen Kenangil, B.C. Ari, F. Altuntas Kaya, M. Demir, F. Mayda Domac (Istanbul, Turkey)

    Objective: Parkinson’s Disease is a neurodegenerative disorder caused by oxidative stress, protein changes and mitochondrial disfunction. Lately, it has been suggested that inflammatory cytokine levels…
  • 2018 International Congress

    Determination of falling direction in Parkinson’s disease patients using a wearable sensor

    Y. Okuma, H. Mitoma (Izunokuni, Japan)

    Objective: The aim of this study is to objectively detect falls and their direction in Parkinson’s disease (PD) patients during everyday activities. Background: Falling is…
  • 2018 International Congress

    Bone health and laboratorial correlations of Vitamin D in Parkinson’s disease

    L. Leandro, C. Moreira, H. Teive (Curitiba, Brazil)

    Objective: To evaluate the correlation between levels of 25 (OH)D (Vitamin D) and Bone Mineral Density (BMD) in a parkinsonian population. Background: Considering a limiting…
  • 2018 International Congress

    Soluble TREM2 and Central and Peripheral Inflammatory Biomarkers in Parkinson’s Disease

    L. Bekris, M. Khrestian, Y. Shao, H. Fernandez, J. Leverenz (Cleveland, OH, USA)

    Objective: Given that Parkinson's disease (PD) may be associated with TREM2 and given that a soluble TREM2 (sTREM2) isoform has been described as elevated in…
  • 2018 International Congress

    Deletion of GBA2 in neuronopathic Gaucher’s disease medaka can’t rescue the phenotype

    E. Nakanishi, N. Uemura, H. Akiyama, M. Kinoshita, H. Yamakado, S. Takeda, Y. Hirabayashi, R. Takahashi (Kyoto, Japan)

    Objective: This study was performed to determine the pathological role of GBA2 in the CNS in GD and GBA1-related PD. Background: Parkinson’s disease (PD) is…
  • 2018 International Congress

    Properties of oscillatory neuronal activity in the basal ganglia and thalamus in patients with Parkinson’s disease

    P. Zhuang, M. Hallett, G. Du, Y. Zhang, Y. Li (Beijing, China)

    Objective: To characterize the firing rate and pattern of oscillatory neurons in basal ganglia and thalamus in patients with Parkinson’s disease (PD). Background: The cardinal…
  • 2018 International Congress

    Activation of chaperone-mediated autophagy reduces oligomeric alpha-synuclein accumulation in LRRK2(R1441G) knockin mouse model of Parkinson’s disease (PD)

    P.W.L. Ho, C.S.C. Lam, M.C.T. Leung, S.Y.Y. Pang, H.F. Liu, L. Li, M.H.W. Kung, D. Ramsden, SL. Ho (Hong Kong)

    Objective: To determine age-dependent accumulation of oligomeric alpha-synuclein in the brain of aged LRRK2(R1441G) knockin mice; and to explore whether activation of chaperone-mediated autophagy (CMA)…
  • 2018 International Congress

    Serum glutamate is associated with the motor subtype of Parkinson’s disease

    A. Latypova, I. Mironova, O. Izhboldina, I. Zhukova, N. Zhukova, E. Kolupaeva (Tomsk, Russian Federation)

    Objective: We aimed to study the concentration of glutamate in the serum of patients with Parkinson's disease (PD) and its connection with clinical variants of…
  • 2018 International Congress

    Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations

    B. Mondal, R. Banerjee, K. Chatterjee, A. Roy, S. Shubham, P. Basu, S. Choudhury, H. Kumar (Kolkata, India)

    Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…
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