Longitudinal cognitive variability in isolated and probable REM sleep behaviour disorder using the Trail Making Test
Objective: To evaluate whether longitudinal changes in cognitive performance are present in isolated REM sleep behaviour disorder (iRBD) and probable RBD (pRBD, positive single-item RBD…Coupling of Cholinergic and Dopaminergic Terminal Loss in Progressive Supranuclear Palsy: A Multimodal [18F]FEOBV and [11C]PE2I Study
Objective: To describe the relationships between dopaminergic and cholinergic terminal deficits in Progressive Supranuclear Palsy (PSP) relative to age-matched Normal controls (NC). Background: There is…Speech Impairment Severity and Motor Symptom Lateralisation in Advanced Parkinson’s Disease
Objective: To determine whether speech impairment severity, as quantified by acoustic speech measures, is associated with motor symptom lateralisation in advanced Parkinson’s disease (PD). Background:…Healthcare Resource Utilization and Associated Costs in Adults with Isolated Dystonia in the United States
Objective: To evaluate all-cause healthcare resource utilization (HCRU) and costs in adults with isolated dystonia in the United States. Background: Isolated dystonia is a rare,…Opsoclonus-Myoclonus-Ataxia Syndrome in Adults: Case Series in Vietnam
Objective: To describe the clinical features, diagnostic findings, and treatment outcomes of adult OMAS cases in Vietnam. Background: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neurological…An observational study of segmental and generalized isolated dystonia to inform development of new drug therapies
Objective: The goal of this study is to characterize severity and variability of symptoms in people with segmental, multifocal, or generalized isolated dystonia. Standardized data…Assessing Concordance Between Clinical judgment And 5-2-1 Criteria In Advanced Parkinsons Disease
Objective: 1. Assess how accurately clinicians diagnose Advanced Parkinson’s Disease (APD) in a routine clinical setting2. Evaluate concordance between 5-2-1 criteria and clinician judgement, including…Tailoring Exergame-Based Training to Parkinson’s Disease: Qualitative insights from Clinicians, Relatives, and Technology Experts
Objective: To explore and describe the perspectives of relatives of people with Parkinson’s Disease (PD), healthcare professionals, as well as digital health technology experts on…Extracellular vesicle–based characterization of synaptic dysfunction in early Parkinson’s disease
Objective: To establish a method that allows for investigating early synaptic dysfunction in Parkinson’s disease (PD) by analyzing CNS-derived extracellular vesicles and assessing their effects…Proposed cognitive indices for the Parkinson’s Progression Markers Initiative
Objective: To propose cognitive indices for the PPMI cognitive battery (PPMI-CB). Background: Cognitive batteries provide meaningful information about Parkinson-related cognitive impairment but are complicated when…
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