Influence of disease stage upon real-world turning performance in people with Parkinson’s
Objective: To explore the influence of disease stage on real-world turning in people with Parkinson’s disease (PD). Background: Turning can be challenging in PD due…Describing Factors Associated with Progression in Parkinson’s Disease: A Retrospective Chart Review
Objective: To describe differences in sociodemographic and clinical profiles between patients with Parkinson’s disease (PD) who remain at Hoehn and Yahr (HY) stage 1–2 up…An Elevation in the Serum Biomarker pTau-181 May Identify Progressive Supranuclear Palsy Pathology
Objective: To report three cases of progressive supranuclear palsy (PSP) with significantly elevated pTau-181 levels on serum testing. Background: According to the MDS-endorsed PSP Study…Optimal and invariant hierarchical cognitive indices in the Parkinson’s Progression Markers Initiative
Objective: To expand cognitive indices derived from PPMI cognitive battery (PPMI-CB) by testing hierarchical models and measurement invariance across pertinent groups. Background: Parkinson’s can cause…Intersectin-1 (ITSN1) Loss-of-Function Variants in Parkinson’s Disease: Clinical Phenotypes and Neuropathological Insights
Objective: To examine the clinical and neuropathological features of carriers of loss-of-function (LoF) variants in ITSN1. Background: Intersectin-1 (ITSN1) is a large multidomain protein involved…Advancing Mobility-Related Activities of Daily Living Monitoring in Parkinson’s Disease: A Systematic Review of Wearable Sensor Technologies
Objective: To systematically review current evidence on wearable sensor devices for the objective monitoring of mobility-related ADLs in patients with PD. Background: Detecting Activities of…Midbrain Hypometabolism in Idiopathic REM Sleep Behavior Disorder Detected by [18F]-FDG PET as a Potential Biomarker of Nigral degeneration
Objective: The aim of this study was to investigate whether midbrain hypometabolism can already be detected in iRBD patients using [18F]-FDG PET scans. Background: Parkinson’s…Levodopa Responsiveness and Motor Complication Trajectories in Parkinson’s Disease by α-Synuclein Seed Amplification Assay Status
Objective: To investigate whether longitudinal trajectories of medication responsiveness and motor complications differ based on cerebrospinal fluid α-synuclein seed amplification assay (CSF SAA) status in…Physical Proximity Influences Mobility in Advanced Parkinson’s Disease Patient–Caregiver Dyads.
Objective: To investigate the relationship between physical proximity within advanced Parkinson’s disease (PD) patient–caregiver dyads and the mobility of each dyad member during daily life.…Assessing Concordance Between Clinical judgment And 5-2-1 Criteria In Advanced Parkinsons Disease
Objective: 1. Assess how accurately clinicians diagnose Advanced Parkinson’s Disease (APD) in a routine clinical setting2. Evaluate concordance between 5-2-1 criteria and clinician judgement, including…
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