Rice bran extract against animal model of Huntington’s disease: Possible role of neurotransmitters
Objective: The present study has been designed to explore the effect of rice bran extract against 3-NP induced neurotoxicity in rats. Background: Huntington’s disease (HD)…Huntington’s disease in the Republic of Tatarstan, epidemiological features
Objective: To evaluate the epidemiological features of Huntington's disease (HD) according to the Centre for Movement Disorders and Botulinum Therapy of Republic of Tatarstan (Centre…)…A retrospective analysis of clinical forms and age of onset of biallelic Huntington disease patients from an Argentinean Center
Objective: To compare AO and clinical presentation in Argentinean bi-allelic (BHD) patients, ie one mutated allele and one either intermediate (IA, 27-35 CAG repeats) or…Down-regulation of miR-9* in the peripheral leukocytes of Huntington’s Disease patients
Objective: To determine whether the alterations of microRNA expression in central nervous tissues can be detected in peripheral leukocytes in Huntington's disease (HD) patients. Background: Huntington’s…The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…Screening of cognitive impairment in Huntington’s disease with the Parkinson’s Disease – Cognitive Rating Scale (PD-CRS)
Objective: To explore the psychometric properties of the PD-CRS as compared to two commonly used measures (the MMSE and the UHDRS Cognitive score) for detecting…Predictors for psychosis in Huntington’s disease: preliminary analysis of the Enroll-HD database.
Objective: To evaluate predictors for psychosis in HD. Background: Behavioral problems are present across all stages of HD, even preceding the development of the motor…Examining central cognitive processing speed as an early marker of Huntington’s disease (HD) onset
Objective: To examine central processing speed as an early marker of Huntington’s disease (HD) onset using the Computerized Test of Information Processing (CTiP). Background: The CTiP,…Huntington’s Disease: Determinants for Cognitive Disease Progression – A Proposed Model
Objective: To develop a conceptual model to determine the rate of cognition impairment in Huntington's disease manifest patients and to identify the factors that influence…Huntington’s Disease Regulatory Science Consortium (HD-RSC): Enabling Pathways to Effective Treatments Through Regulatory Science and Innovation
Objective: To establish a broad-based consortium, the Huntington’s Disease Regulatory Science Consortium (HD-RSC), which will advance disease specific data standards and drug development tools, as…
