Dynamic prediction of motor diagnosis in Huntington’s disease using a joint modeling approach
Objective: Compare various clinical and biomarker trajectories for tracking Huntington's disease (HD) progression and predicting motor conversion. Background: Huntington’s disease (HD) is a fatal neurodegenerative disease…Demographic and Clinical Characteristics and Tetrabenazine (TBZ) Persistence in Patients With Huntington Disease (HD)-Associated Chorea
Objective: To characterize demographic and clinical characteristics of HD patients with chorea based on TBZ use status, and to examine treatment persistence with TBZ in…Efficacy, Safety, and Tolerability of Pridopidine in Huntington Disease (HD): Results From the Phase II Dose-Ranging Study, Pride-HD
Objective: To assess efficacy, safety, and tolerability of multiple doses of pridopidine in HD patients (pts) with signs of motor dysfunction. Background: Prior trials suggested…Clinical and genetic characterization of Huntington’s disease in relation to the age and type of onset.
Objective: To describe the clinical features and CAG repeats in a large population of Mexican patients with Huntington's disease and its relation to the age…Prescription pattern of treatment in Mexican patients with Huntington’s Disease.
Objective: To describe the prescription pattern for the treatment of HD in a sample of Mexican patients from a tertiary referral center. Background: Huntington’s disease…Prevalence of substance abuse in Huntington´s disease patients and its relationship with neuropsychiatric symptoms
Objective: To describe the prevalence of substance abuse and its relationship with neuropsychiatric features in Huntington’s disease (HD). Background: Substance abuse is not well established…Baseline multimodal information predicts future motor impairment in premanifest Huntington’s disease
Objective: To evaluate the prognostic accuracy of structural magnetic resonance imaging and genetic-based measures in premanifest Huntington’s disease for estimating future motor impairment. Background: Despite…Evidence-based Brazilian Physicaltherapy Guideline for Huntington´s Disease
Objective: Identify the Evidence based Physicaltherapy available for HD and provide recommendations to physicians Background: In Huntington’s Disease (HD) Chorea is usually presented in any phase…Factors Influencing Completion of Predictive Testing for Huntington’s Disease (HD)
Objective: To determine if the new simplified testing protocol led to an increase in completion rate of predictive testing for HD, and to study some…Sensory modulation of postural control in Huntington’s disease
Objective: To characterize sensory modulation of postural control in Huntington's disease (HD); and to identify postural metrics that are sensitive in the prodromal stage of…
